Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu +3 more
wiley +1 more source
Treating prolonged grief disorder with CBT for insomnia: A replicated single-case experimental study protocol. [PDF]
de Lang TA +4 more
europepmc +1 more source
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley +1 more source
Effects of digital cognitive-behavioral therapy for insomnia in heavy drinkers with insomnia: A replication and extension study. [PDF]
Verlinden JJ +6 more
europepmc +1 more source
The association between sleep disturbance and stimulant use: A cross‐lagged examination
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian +12 more
wiley +1 more source
The Sleep Symptoms Are Directly Associated With Suicide Risk in Adolescents and Youth Patients With Depression. [PDF]
Zheng Y, Yuan S, Zhang J, Ma Y, He H.
europepmc +1 more source
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Nature- based nursing intervention: the impact on insomnia and feeling of hopelessness among patients with depression at Nour El-Hikma psychiatric hospital, Egypt (A controlled quasi- experimental study). [PDF]
Radwan HA +3 more
europepmc +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Causal Associations Between Sleep Traits and Polycystic Ovary Syndrome: A Univariable, Bidirectional, and Multivariable Mendelian Randomization Study. [PDF]
Chen X +7 more
europepmc +1 more source

