Results 51 to 60 of about 34,475 (222)
Charting the landscape of the environmental exposome
We describe the biological and chemical components of the environmental exposomes in three major environmental matrices that are highly relevant to human and social‐economical health—air, soil, and water. We discuss how different exposome components can interact with each other. Finally, we propose a list of outstanding challenges to be tackled to push
Xin Wei+6 more
wiley +1 more source
The burden of untreated insomnia disorder in a sample of 1 million adults: a cohort study
Background Insomnia disorder is a highly prevalent, significant public health concern associated with substantial and growing health burden. There are limited real-world data assessing the burden of insomnia disorder on daytime functioning and its ...
Michael Grandner+5 more
doaj +1 more source
Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong+7 more
wiley +1 more source
The Relationship between Depression and Insomnia Symptoms Amongst a Sample of UK University Students [PDF]
Research exploring the relationship between mental health difficulties and insomnia amongst students in the UK remains limited. This study further examined the extent of potential relationships between insomnia, anxiety and depression symptoms amongst ...
Umair Akram+6 more
doaj +1 more source
Sleep syndromes onset detection based on automatic sleep staging algorithm [PDF]
In this paper, we propose a novel method and a practical approach to predicting early onsets of sleep syndromes, including restless leg syndrome, insomnia, based on an algorithm that is comprised of two modules. A Fast Fourier Transform is applied to 30 seconds long epochs of EEG recordings to provide localized time-frequency information, and a deep ...
arxiv
Automated Detection of Isolated REM Sleep Behavior Disorder Using Computer Vision
Objective Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is, in most cases, an early stage of Parkinson's disease or related disorders. Diagnosis requires an overnight video‐polysomnogram (vPSG), however, even for sleep experts, interpreting vPSG data is challenging.
Mohamed Abdelfattah+11 more
wiley +1 more source
Clinical practice guidelines for insomnia disorder
Insomnia disorder is defined as difficulty in falling asleep, maintaining sleep, and early morning awakenings. Common daytime consequences experienced are fatigue, mood instability and impaired concentration.
Lucille Malan, Nokuthula Dlamini
doaj +1 more source
Severity of light pollution and its multifaceted impact: A mini review on the dark side of light [PDF]
There is a surging concern regarding the adverse effects of light pollution on human well-being. This manuscript aims to emphasise the deleterious effects of uncontrolled night-light exposure on the health and mood of individuals residing in a highly populated elite metropolitan society compared to those residing in remote villagesin a scattered manner.
arxiv
Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner+4 more
wiley +1 more source
TransCon PTH is an investigational once‐daily prodrug providing sustained release of active PTH designed to maintain stable PTH levels in the physiological range for 24 hours/day. The PaTHway trial met all primary and key secondary endpoints with statistically significant differences from placebo. Most adverse events (AEs) were mild/moderate. Injection‐
Aliya A Khan+19 more
wiley +1 more source