Results 51 to 60 of about 34,475 (222)

Charting the landscape of the environmental exposome

open access: yesiMeta, Volume 1, Issue 4, December 2022., 2022
We describe the biological and chemical components of the environmental exposomes in three major environmental matrices that are highly relevant to human and social‐economical health—air, soil, and water. We discuss how different exposome components can interact with each other. Finally, we propose a list of outstanding challenges to be tackled to push
Xin Wei   +6 more
wiley   +1 more source

The burden of untreated insomnia disorder in a sample of 1 million adults: a cohort study

open access: yesBMC Public Health, 2023
Background Insomnia disorder is a highly prevalent, significant public health concern associated with substantial and growing health burden. There are limited real-world data assessing the burden of insomnia disorder on daytime functioning and its ...
Michael Grandner   +5 more
doaj   +1 more source

Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong   +7 more
wiley   +1 more source

The Relationship between Depression and Insomnia Symptoms Amongst a Sample of UK University Students [PDF]

open access: yesSleep Medicine Research, 2019
Research exploring the relationship between mental health difficulties and insomnia amongst students in the UK remains limited. This study further examined the extent of potential relationships between insomnia, anxiety and depression symptoms amongst ...
Umair Akram   +6 more
doaj   +1 more source

Sleep syndromes onset detection based on automatic sleep staging algorithm [PDF]

open access: yesarXiv, 2021
In this paper, we propose a novel method and a practical approach to predicting early onsets of sleep syndromes, including restless leg syndrome, insomnia, based on an algorithm that is comprised of two modules. A Fast Fourier Transform is applied to 30 seconds long epochs of EEG recordings to provide localized time-frequency information, and a deep ...
arxiv  

Automated Detection of Isolated REM Sleep Behavior Disorder Using Computer Vision

open access: yesAnnals of Neurology, EarlyView.
Objective Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is, in most cases, an early stage of Parkinson's disease or related disorders. Diagnosis requires an overnight video‐polysomnogram (vPSG), however, even for sleep experts, interpreting vPSG data is challenging.
Mohamed Abdelfattah   +11 more
wiley   +1 more source

Clinical practice guidelines for insomnia disorder

open access: yesSouth African Family Practice, 2017
Insomnia disorder is defined as difficulty in falling asleep, maintaining sleep, and early morning awakenings. Common daytime consequences experienced are fatigue, mood instability and impaired concentration.
Lucille Malan, Nokuthula Dlamini
doaj   +1 more source

Severity of light pollution and its multifaceted impact: A mini review on the dark side of light [PDF]

open access: yesarXiv, 2023
There is a surging concern regarding the adverse effects of light pollution on human well-being. This manuscript aims to emphasise the deleterious effects of uncontrolled night-light exposure on the health and mood of individuals residing in a highly populated elite metropolitan society compared to those residing in remote villagesin a scattered manner.
arxiv  

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

open access: yesAnnals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner   +4 more
wiley   +1 more source

Efficacy and Safety of Parathyroid Hormone Replacement With TransCon PTH in Hypoparathyroidism: 26‐Week Results From the Phase 3 PaTHway Trial

open access: yesJournal of Bone and Mineral Research, Volume 38, Issue 1, Page 14-25, January 2023., 2023
TransCon PTH is an investigational once‐daily prodrug providing sustained release of active PTH designed to maintain stable PTH levels in the physiological range for 24 hours/day. The PaTHway trial met all primary and key secondary endpoints with statistically significant differences from placebo. Most adverse events (AEs) were mild/moderate. Injection‐
Aliya A Khan   +19 more
wiley   +1 more source

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