Results 81 to 90 of about 204,509 (311)
Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu +4 more
wiley +1 more source
Empirically Testing the Neurocognitive Model of Insomnia [PDF]
The Neurocognitive Model of insomnia proposes that, through conditioned arousal, individuals with insomnia may experience heightened cortical arousal leading to increased sensory processing of external stimuli and sleep state misperception.
Sharman, Rachel
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Development and Validation of a Pediatric Insomnia Composite
, 2020 Insomnia affects approximately 20-30% of children with consequences on daytime functioning, academic performance, social functioning, and quality of life.
Parkhill, David
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Hubungan Insomnia Dengan Timbulnya Acne Vulgaris Di D’risya Skin Care Clinic Medan [PDF]
, 2018 Pendahuluan : Acne Vulgaris adalah penyakit kulit kronis yang terjadi akibat peradangan menahun pilosebasea yang ditandai dengan adanya komedo, pustul, nodul dan kista.
Novika, Reisha
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Gephyrin Neurological Autoimmunity
Annals of Neurology, EarlyView.Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano +10 more
wiley +1 more source
Insomnia associated with depressive disorder: Primary, secondary, or mixed?
Indian Journal of Psychological Medicine, 2011 Background: Insomnia is a common problem that is known to occur during depression. However, literature still debates whether insomnia is part of depression or a separate entity.
Ravi Gupta, Vivekananda Lahan
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann +10 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Emotion dysregulation in insomnia disorder: the possible role of psychiatric comorbidity
Frontiers in SleepAimThe purpose of this study was to investigate the link between emotion dysregulation and insomnia disorder as well as the possible role of psychiatric comorbidity on the association.
Markus Jansson-Fröjmark, Samiul Hossain
doaj +1 more source
Electromagnetictherapy for Treatment of Insomnia: A clinical Trial Study [PDF]
Background & Objectives: Insomnia is one of the most common sleep disorders in the world. It causes disruption in daily activities and increases the risk of major depression.
رستمی, امیر مسعود +5 more
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