Results 111 to 120 of about 8,901,503 (263)

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello   +10 more
wiley   +1 more source

Newbrook Lodge Nursing Home, 680, Inspection Report, 25 May 2016

open access: yes, 2017
Inspection date: 25 May ...
Crowe, Leanne   +1 more
core  

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

CareChoice Clonakilty, 230, Inspection Report, 22 June 2016

open access: yes, 2017
Inspection date: 22 Jun ...
Connelly, Caroline
core  

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

Organization & work of the inspection services: team work and assignment

open access: yesAvances en Supervisión Educativa, 2014
Despite inspectors have been evaluating and assessing schools in Spain for more than 160 years, there is still a need of analysis and debate on how we are expected to unify criteria to improve our job.
Dolores Carrasco Arauz
doaj  

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan   +4 more
wiley   +1 more source

Cara Care Centre, 735, Inspection Report, 11 March 2016

open access: yes, 2017
Inspection date: 11 Mar ...
Rafferty, Nuala, Ewings, Leone
core  

Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit   +10 more
wiley   +1 more source

A Macro-to-Micro Framework for Bridge-Deck Pavement-Distress Inspection Using LiDAR-Based Screening and YOLOv8s Image Detection: A Case Study of the Jingzhou Yangtze River Highway Bridge and Public Benchmark Data

open access: yesSensors
Timely bridge-deck pavement inspection must cover large areas while preserving the image detail needed to recognize local distress. This study develops a macro-to-micro workflow with separate LiDAR screening and YOLOv8s image-detection branches. Airborne
Yadong Huang   +6 more
doaj   +1 more source

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