Results 21 to 30 of about 156,310 (309)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

La direttiva INSPIRE: le data specifications [PDF]

open access: yes, 2022
Questa tesina tratta delle specifiche sui dati della direttiva INSPIRE: essa fa una panoramica della direttiva inspire per poi focalizzarsi sulle data specifications dei temi dell'Annex 1.
Penzo, Alessandro
core  

Mapping Seafloor Sediment Distributions Using Public Geospatial Data and Machine Learning to Support Regional Offshore Renewable Energy Development

open access: yesGeosciences
Given the rapid expansion of offshore wind development in the United States (US), the accurate mapping of benthic habitats, specifically surficial sediments, is essential for mitigating potential impacts on these valuable ecosystems.
Connor W. Capizzano   +5 more
doaj   +1 more source

Information about real estate – a comparative study of Poland and Latvia [PDF]

open access: yesGeodesy and Cartography, 2019
Each European Union Member State keeps a register of data on properties located in its territory. The number, type and scope of these properties are determined by each Member State’s needs. The INSPIRE Directive enables the scope of data to be harmonised,
Katarzyna Kocur-Bera, Velta Parsova
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Idmb: a tool for navigating the Inspire data model and generating an Inspire SQL database and WFS Configuration [PDF]

open access: yes, 2014
The Inspire Data Model Browser (IDMB) is a free tool that performs the following functions: (i) it presents the Inspire UML Data Model as a tree-based structure, which is complementary to the UML diagrams; (ii) it generates a Postgis SQL Script for ...
Belussi, A.   +5 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Complementary relationships between entanglement and measurement

open access: yesAcademia Quantum
Complementary relationships exist among interference properties of particles such as pattern visibility, predictability, and distinguishability.
Michael Steiner, Ronald Rendell
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Informazioni ambientali sempre più condivise

open access: yesGEOmedia, 2010
SEIS: Shared Enviroment and Information System The Shared Environmental Information System (SEIS) is a collaborative initiative of the European Commission and the European Environment Agency (EEA) to establish together with the Member States an ...
Mauro Salvemini
doaj  

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