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Endogenous DNA Damage as a Source of Genomic Instability in Cancer
André Nussenzweig
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Microsatellite instability in cancer of the proximal colon.
Science, 1993Colorectal tumor DNA was examined for somatic instability at (CA)n repeats on human chromosomes 5q, 15q, 17p, and 18q. Differences between tumor and normal DNA were detected in 25 of the 90 (28 percent) tumors examined.
S. Thibodeau, G. Bren, D. Schaid
semanticscholar +1 more source
Orthopedic Clinics of North America, 2000
Posterior shoulder instability is a pathology that is increasingly seen in athletes. Excessive capsular laxity was originally proposed as the key component. Recent cadaveric and arthroscopic work has identified the importance of glenolabral integrity and glenoid depth in maintaining glenohumeral stability.
J, Antoniou, D T, Harryman
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Posterior shoulder instability is a pathology that is increasingly seen in athletes. Excessive capsular laxity was originally proposed as the key component. Recent cadaveric and arthroscopic work has identified the importance of glenolabral integrity and glenoid depth in maintaining glenohumeral stability.
J, Antoniou, D T, Harryman
openaire +2 more sources
, 1991
A broad class of astronomical accretion disks is presently shown to be dynamically unstable to axisymmetric disturbances in the presence of a weak magnetic field, an insight with consequently broad applicability to gaseous, differentially-rotating ...
S. Balbus, J. Hawley
semanticscholar +1 more source
A broad class of astronomical accretion disks is presently shown to be dynamically unstable to axisymmetric disturbances in the presence of a weak magnetic field, an insight with consequently broad applicability to gaseous, differentially-rotating ...
S. Balbus, J. Hawley
semanticscholar +1 more source
Unanticipated shocks could lead to instability, which is reflected in statistically significant changes in distributions of independent Gaussian random variables. Changes in the conditional moments of stationary variables are predictable. We provide a framework based on a statistic for the Sample Generalized Variance, which is useful for interrogating ...
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A habitus of instability: youth homelessness and instability [PDF]
This research introduces the concept of a habitus of insecurity to account for the lives of homeless young people. It outlines how conditions of existence are internalised and how homeless young people come to expect and in turn recreate instability in their lives.
openaire +3 more sources