Results 191 to 200 of about 1,063,077 (278)

A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis

open access: yesAdvanced Science, EarlyView.
This study presents RotEx‐LAMP‐LFA, a fully integrated, battery‐powered, low‐cost point‐of‐care device for rapid cervical cancer risk detection based on HPV16/18 E6/E7 mRNA. Clinically validated, the system demonstrated high sensitivity and specificity, and showed full concordance between self‐collected and clinician‐collected samples, offering a ...
Yuan Gao   +10 more
wiley   +1 more source

Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li   +11 more
wiley   +1 more source

Comparative Evaluation of Esthetic Zirconia Crowns in Children: A Comprehensive Review. [PDF]

open access: yesCureus
Alrassan AM   +13 more
europepmc   +1 more source

Microstructural Insights Into LATP Ceramic Nanofibers for High‐Performance Quasi‐Solid‐State Batteries

open access: yesAdvanced Science, EarlyView.
A sustainable electrospinning technique produces LATP ceramic nanofibers that form continuous Li⁺‐conductive pathways within composite solid electrolytes. The resulting quasi‐solid‐state batteries combine the strength of ceramic nanofibers with the flexibility of polymers, delivering high critical current density and excellent rate performance at room ...
Sivaraj Pazhaniswamy   +3 more
wiley   +1 more source

Scapholunate Ligament Injuries. [PDF]

open access: yesJ Hand Surg Glob Online
Zhou JY, Jodah R, Joseph LP, Yao J.
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

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