Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian +10 more
wiley +1 more source
On-Ground Calibration of a Nano-G Accelerometer for Micro-Vibration Monitoring in Space on a Dual-Axis Indexing Device. [PDF]
Zhou Y, Li Z, Xu Q, Li X.
europepmc +1 more source
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
Enhanced Electromagnetic Ultrasonic Thickness Measurement with Adaptive Denoising and BVAR Spectral Extrapolation. [PDF]
Ma L, Guo X, Zhou S, Li X, Ouyang X.
europepmc +1 more source
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Experimental study of a cryogenic pneumatic thrower for launching soft projectiles in avalanche protection. [PDF]
Tasmukhanova A +10 more
europepmc +1 more source
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen +9 more
wiley +1 more source
Survival Models for Predictive Maintenance and Remaining Useful Life in Sensor-Enabled Smart Energy Networks: A Review. [PDF]
Shadi MR +3 more
europepmc +1 more source
Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi +16 more
wiley +1 more source
Fault Detection and Isolation of MEMS IMU Array Based on WOA-MVMD-GLT. [PDF]
Li H, Sun F, Tian J, He X, Zhu T.
europepmc +1 more source

