Results 111 to 120 of about 968,733 (291)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

TSNET: A solid waste instance segmentation model in China based on a Two-Step detection strategy and satellite remote sensing images

open access: yesInternational Journal of Applied Earth Observations and Geoinformation
Due to the concealment and randomness of solid waste disposal sites, the time and manpower costs for manual on-site inspections or remote sensing visual interpretation are significantly increased.
Jiaqi Yu   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Object-Guided Instance Segmentation for Biological Images

open access: yes, 2020
Instance segmentation of biological images is essential for studying object behaviors and properties. The challenges, such as clustering, occlusion, and adhesion problems of the objects, make instance segmentation a non-trivial task.
Tang, Hui   +7 more
core   +1 more source

PlantSegNeRF: A few-shot, cross-species method for plant 3D instance point cloud reconstruction via joint-channel NeRF with multi-view image instance matching

open access: yesArtificial Intelligence in Agriculture
Organ segmentation of plant point clouds is a prerequisite for the high-resolution and accurate extraction of organ-level phenotypic traits. Although the fast development of deep learning has boosted much research on segmentation of plant point clouds ...
Xin Yang   +9 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Audio-Visual Instance Segmentation

open access: yes2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
Accepted by CVPR ...
Ruohao Guo   +13 more
openaire   +2 more sources

An Effective Strategy of Object Instance Segmentation in Sonar Images

open access: yesIET Signal Processing
Instance segmentation is a task that involves pixel-level classification and segmentation of each object instance in images. Various CNN-based methods have achieved promising results in natural image instance segmentation. However, the noise interference,
Pengfei Shi   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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