β‐Triketone‐Based Ionizable Cationic Lipids Synthesized via Click Chemistry for siRNA Delivery
This study innovatively applies β‐triketone‐based click chemistry in the synthesis of ionizable cationic lipids (ICLs), which allows the generation of a lipid library in large quantities and in a short time. The ICLs identified achieved effective lipid nanoparticles‐mediated hepatic gene silencing in vivo using siRNA, and computational simulations are ...
Huatian Li +7 more
wiley +1 more source
Kinematic and aerodynamic modeling of flexible wings with wing root adjustment for flapping wing micro aerial vehicles. [PDF]
Liu Z, Zhang X, Wang Z, Ye R.
europepmc +1 more source
Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu +15 more
wiley +1 more source
Age-group differences between young and middle-aged adults in spatiotemporal EEG dynamics revealed by instantaneous frequency microstate analysis. [PDF]
Nobukawa S +3 more
europepmc +1 more source
2D Copper MOF Membranes with Precise Pores for Ionic Memory
. ABSTRACT Biological ion channels play a critical role in the complex physiological processes of living organisms. Inspired by these natural systems, we demonstrate the fabrication of ultrathin 2D copper‐based metal‐organic framework (CuMOF) films and their application to mimic key functionalities of biological membranes. Using a liquid–air interface
Hiran Jyothilal +9 more
wiley +1 more source
Exploratory Correlation Analysis of Respiratory Waveform, Instantaneous Respiratory Depth and Rate in Relation to Parasympathetic Indices During Spontaneous Breathing. [PDF]
Yagishita H, Tanabe S, Sato H.
europepmc +1 more source
Solid Harmonic Wavelet Bispectrum for Image Analysis
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source
Quantifying coupling and causality in dynamic bivariate systems: a unified framework for time-domain, spectral, and information-theoretic analysis. [PDF]
Sparacino L +6 more
europepmc +1 more source
Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin +2 more
wiley +1 more source
Alpha frequency shapes perceptual sensitivity by modulating optimal phase likelihood. [PDF]
Romei V, Tarasi L.
europepmc +1 more source

