Fractional Flow Reserve and Instantaneous Wave‐Free Ratio Predict Pathological Wall Shear Stress in Coronary Arteries: Implications for Understanding the Pathophysiological Impact of Functionally Significant Coronary Stenoses [PDF]
Background The pathophysiological mechanism behind adverse outcomes associated with ischemia‐inducing epicardial coronary stenoses and microcirculatory dysfunction remains unclear. Wall shear stress (WSS) plays an important role in atherosclerotic plaque
Christopher C. Y. Wong +8 more
doaj +2 more sources
The reasons why fractional flow reserve and instantaneous wave-free ratio are similar using wave separation analysis [PDF]
Background and objectives Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are the two most commonly used coronary indices of physiological stenosis severity based on pressure. To minimize the effect of wedge pressure (P wedge ), FFR
Soohong Min +3 more
doaj +2 more sources
Fractional Flow Reserve Versus Instantaneous Wave‐Free Ratio in Assessment of Lesion Hemodynamic Significance and Explanation of their Discrepancies. International, Multicenter and Prospective Trial: The FiGARO Study [PDF]
Background The FiGARO (FFR versus iFR in Assessment of Hemodynamic Lesion Significance, and an Explanation of Their Discrepancies) trial is a prospective registry searching for predictors of fractional flow reserve/instantaneous wave‐free ratio (FFR/iFR)
Tomas Kovarnik +23 more
doaj +2 more sources
Patients with multivessel coronary artery disease require an individual approach when choosing tactics for myocardial revascularization. In some cases, additional methods for assessing the stenosis significance should be used, such as measuring the ...
F. B. Shukurov +4 more
doaj +3 more sources
Pathophysiological factors contributing to fractional flow reserve and instantaneous wave-free ratio discordance [PDF]
The diagnostic accuracy and clinical benefits of instantaneous wave-free ratio (iFR) compared to fractional flow reserve (FFR) have been well-established in the literature. Despite the advantages of non-hyperemic pressure indices, approximately 20% of
Benjamin Fogelson +3 more
doaj +4 more sources
Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI [PDF]
BACKGROUND: Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone.
Al-Lamee, R +6 more
core +12 more sources
Dataset on blood flow and instantaneous wave-free ratio in normal and stenosed coronary arteries [PDF]
Instantaneous wave-free ratio (iFR) has been proposed as a hemodynamic parameter that can reliably reflect the blood flow in stenosed coronary arteries. Currently, there are few investigations on the quantitative analysis of iFR in the patients regarding
Haipeng Liu +9 more
doaj +2 more sources
Impact of target coronary artery stenosis severity measured by instantaneous wave-free ratio on to bypassed graft patency [PDF]
Background: This study aimed to assess the impact of the measurement of the degree of target coronary artery stenosis using the instantaneous wave-free ratio (iFR) on patency of attached grafts.
Almas Tolegenuly +2 more
doaj +2 more sources
Hybrid Instantaneous Wave-Free Ratio–Fractional Flow Reserve versus Fractional Flow Reserve in the Real World [PDF]
BackgroundThe instantaneous wave-free ratio (iFR) is a novel method to assess the ischemic potential of coronary artery stenoses. Clinical trial data have shown that iFR has acceptable diagnostic agreement with fractional flow reserve (FFR), the ...
Kara Shuttleworth +5 more
doaj +2 more sources
Comparative analysis of instantaneous wave-free ratio and quantitative real-time myocardial contrast echocardiography for the assessment of myocardial perfusion [PDF]
Background and hypothesisThe field of coronary artery physiology is developing rapidly and changing the practice of interventional cardiology. A new functional evaluation technique using the instantaneous wave-free ratio (iFR) has become an alternative ...
Li Liang +7 more
doaj +2 more sources

