Results 101 to 110 of about 1,903,000 (307)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A regional process under the international initiative for IFM
E3S Web of Conferences, 2016 Climate change is likely to result in increases in the frequency or intensity of extreme weather events including floods. The International Flood Initiative (IFI), initiated in January 2005 by UNESCO and WMO and voluntary partner organizations has ...
Murase Masahiko +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Institutional Research as Adjunct to University Management
Canadian Journal of Higher Education, 1972 The purposes of this paper are to suggest that university management needs analytical support and to describe an office of institutional research which meets this need. Recent interest in university management has grown because institutions must plan and operate in increasingly complicated circumstances.
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Taking Stock : Measuring Pollution Prevention in Illinois
, 1997 The goals of the Illinois Pollution Prevention Act of 1992 are to reduce disposal and release oftoxic or hazardous materials into the environment and encourage pollution prevention (P2) in Illinois.
Shapiro, Karen +2 more
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Encouraging Research and Publication among Academic Librarians [PDF]
, 2013 Presentation for the 2013 Library Management Institute Summer Conference. This presentation discusses encouraging research and publication among academic librarians. It covers topics on why support is needed, related surveys and methodology, respondents,
Sassen, Catherine
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Expected lifetime range ratio to find mean reversion: Evidence from Indian stock market
Cogent Economics & Finance, 2018 We use the expected lifetime range (ELR) ratio based on the extreme values of asset prices to detect the presence of mean reversion in stock returns.
Muneer Shaik, S. Maheswaran
doaj +1 more source
Quality Management in Research Institutes [PDF]
Pomiary Automatyka Robotyka, 2019 Krzysztof Stefański, Krystyna Chróst
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