Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Knowledge, Attitudes, Practices, Barriers, and Promotional Strategies Related to Clinical Data Interchange Standards Consortium Adoption Among Clinical Data Management Professionals: Semiqualitative Interview Study. [PDF]
Xie G, He J, Ma W, Myint PK, Wu C, Wu Y.
europepmc +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
NBDC key message: Consider downstream costs and benefits of land and water management interventions
This digital story was produced to communicate the key messages resulting from the Nile Basin Development Challenge (NBDC). Key message 7 is to attend to downstream and off-site benefits of rainwater management as well as upstream or on-farm benefits and
International Water Management Institute +1 more
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ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Research and innovation for water security: IWMI strategy 2024–2030. Summary
Water security is essential for a safe, just and sustainable future. The IWMI Strategy 2024–2030 is an ambitious agenda for research and innovation on water security.
International Water Management Institute
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Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Exploring Patient and Caregiver Work and Continuity of Care During Hospital-to-Home Transitions of Care in the Canadian Context. [PDF]
Singh H +11 more
europepmc +1 more source
Freight Mobility Research Institute [PDF]
This is a data management plan for the Freight Mobility Research Institute (FMRI) University Transportation Center (UTC). This data management plan was created in compliance with the US Department of Transportation\u2019s \u201cPlan to Increase Public ...
Florida Atlantic University
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