Results 31 to 40 of about 27,826 (252)

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

A MEASURE OF MARKETING ORIENTATION IN HIGHER LEARNING INSTITUTIONS: A SCALE DEVELOPMENT STUDY

Journal of Applied Structural Equation Modeling, 2022
The world is encountering various challenges and complexities. To many, successful operation in such an environment hinges upon being marketing oriented, which is also a challenge to many higher learning institutions (HLIs). This study intended to devise the best scale that can be used to measure and operationalize marketing orientation in HLIs ...
openaire   +2 more sources

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Military Japanese Studies in the Far East in the Early 20th Century

Ежегодник Япония, 2022
The article is devoted to the problems of the formation and development of military Japanese studies in the early 20th century. Its relevance is related to the fact that current problems of the Russian-Japanese relations are rooted in the political ...
V. G. Datsyshen
doaj   +1 more source

Is Youth's Engagement in Agribusiness an Opportunity or a Necessity? A Closer Look at the Situation in South Kivu, Eastern Democratic Republic of the Congo

Agribusiness, EarlyView.
ABSTRACT Despite the broad focus on necessity‐ and opportunity‐driven entrepreneurship in research and policy, the entrepreneurial dichotomy within the agribusiness context has not been adequately addressed. This study contributes to closing this knowledge gap by examining youth's perceptions of agribusiness through the lens of the push‐pull motivation
Cool Dady Mangole, Paul Martin Dontsop Nguezet, Shiferaw Feleke, Victor Manyong, Kamala Kaghoma Christian, Zoumana Bamba, Tahirou Abdoulaye   +6 more
wiley   +1 more source

Military Japanese Studies in the Russian Far East in the Early 20^th Century

Russian Japanology Review, 2021
The article is devoted to the problems of the formation and development of military Japanese studies in the early 20th century. Its relevance is related to the fact that current problems of the Russian-Japanese relations are rooted in the political ...
V. G. Datsyshen
doaj   +1 more source

The Chinese Studies, their origin and development at the Institute of Oriental studies of the Russian Academy

Orientalistica, 2018
The article offers an account on the history of the Department of Chinese Studies at the Institute of the Oriental Studies of the Russian Academy in 1960-1980. This is one of the most important centres of Chinese Studies in the former USSR and in the post-soviet Russia.
openaire   +1 more source

Development of Entrepreneurial Orientation in Women and Men. A Study from the Institutional Perspective

Economía teoría y práctica, 2019
ندرس الأعباء التنظيمية والمعيارية والمعرفية لتحديد الإطار المؤسسي الحالي، ثم حددنا التأثير المحتمل على التوجه الريادي الفردي، وبالنظر إلى ذلك، تستكشف دراستنا الاختلافات بين ريادة الأعمال من الذكور والإناث من أجل تحديد المشكلة الرئيسية في دور النوع الاجتماعي. كانت منهجيتنا هي تطبيق PLS - SEM لطريقة مقارنة في 250 من رواد الأعمال المكسيكيين. تُظهر النتائج
Neftali Parga-Montoy, Héctor Cuevas-Vargas   +1 more
openaire   +1 more source

Dimensions of the AI Divide: Digital Inequality and Psychological Consequences

AI &Innovation, EarlyView.
ABSTRACT Artificial intelligence (AI) has become a foundational component of contemporary social, economic, and political life. Yet, the ways in which AI reshapes patterns of exclusion beyond questions of access and technical capability remain insufficiently theorized.
Christos Papaioannou
wiley   +1 more source

Justifications for Undertaking Marketing Orientation Studies in Higher Learning Institutions in Tanzania

Makerere Journal of Higher Education, 1970
This paper was written with the major aim of presenting a number of issues which justify the undertaking of marketing orientation studies in Tanzania Higher Learning Institutions (HLIs). It was also the intention of the authors to give a brief picture of marketing practice in Tanzania environment and on the higher learning institutions. The information
Muya, Francis, Tundui, Hawa
openaire   +3 more sources