Results 91 to 100 of about 4,673,170 (295)
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai+2 more
wiley +1 more source
Social Rehabilitation of Minors in the United States of America [PDF]
The United States of America was one of the first countries in the world, which at the turn of the nineteenth and twentieth century took to building the justice and social rehabilitation system for minors.
Agnieszka Barczykowska+1 more
doaj
NORTH AMERICA: An Apache Life‐Way: The Economic, Social, and Religious Institutions of the Chiricahua Indians. M
Ruth Benedict
openalex +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
Fiction as an Institution [PDF]
John Searle and I agree about many important aspects about individual speech acts within fiction. I hope to reduce the area of disagreement by explaining how much work an analysis of fiction as linguistic behavior can do to solve the problems of truth ...
MARTINICH, A. P.
core +1 more source
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi+5 more
wiley +1 more source
Habit, sedimentation and institutions
In contrast to intellectualist and behaviorist conceptions of habit, recent enactivist discussions argue that habits reflect a type of contextualized intelligence.
Shaun Gallagher
doaj +1 more source
A HISTORY OF INSTITUTIONAL CARE OF THE INSANE IN THE UNITED STATES AND CANADA [PDF]
Henry M. Hurd
openalex +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source