Results 61 to 70 of about 527,927 (245)

Operation and Governance of the National Health System of Ecuador

Íconos, 2019
The National Health System of Ecuador (SNS) is characterized by its segmentation and fragmen-tation, which limits the implementation of public policies in the sector and provisional services.
Adriano Molina Guzmán
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Modelling Agent Institutions

, 2013
Everyday uses of the notion of institution and some typical institutions have been studied and formalized by economists and philosophers. Borrowing from these everyday understandings, and influenced by their formalizations, the notion of institution has been used within the agents community to model and implement a variety of socio ...
Fornara, Nicoletta, Lopes Cardoso, Henrique, Noriega, Pablo, Oliveira, Eugenio, Tampitsikas, Charalampos   +4 more
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

BALANCING THE INTERESTS OF EXTERNAL AND INTERNAL BENEFICIARIES IN THE CONTEXT OF INCOMPLETE CONTRACTS IN A RESOURCE ECONOMY

Север и рынок: формирование экономического порядка
This article examines the uncertainties arising from agent interactions in interregional resource-intensive markets, particularly those prevalent in northern regions, and explores factors undermining their effectiveness Given these circumstances, the ...
Oleg V. Tolstoguzov
doaj   +1 more source

What can organisational theory offer knowledge translation in healthcare? A thematic and lexical analysis

BMC Health Services Research, 2018
Background Despite the relative abundance of frameworks and models to guide implementation science, the explicit use of theory is limited. Bringing together two seemingly disparate fields of research, this article asks, what can organisational theory ...
Ann Dadich, Navin Doloswala
doaj   +1 more source

Institutions, Behavior of Agents and Efficiency [PDF]

Journal of Institutional Studies, 2016
We study the efficiency criterion, describing the behavior and choices of agents, the influence of moral norms on the model of behavior, as well as the criterion of efficiency as an institution to assess the behavior and development of the economic system.
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

CORRUPTION AS AN INSTITUTE OF COMMUNICATION IN THE ‘PRINCIPAL – AGENT’ MODEL

Вестник Кемеровского государственного университета, 2015
In terms of the ‘principal-agent model’ corruption can be defined as violation of the contract (formal or informal) between the agent and the principal. The resources provided by the principal are then used by the agent for their private needs. From this
N. К. Dyatlova, Ya. A. Tsader
doaj  

Institutional framework for the Financial Supervision Authority's control over the activities of an insurance agent

Journal of Modern Science
Objectives The subject of consideration is the supervisory powers of the Financial Supervision Authority in terms of the control of insurance agents. Act of 15 Dec 2017 on Insurance Distribution introduced the possibility of conducting inspections of ...
Mariusz Bidziński, Bogusław Ulijasz
doaj   +1 more source