Results 71 to 80 of about 527,927 (245)
Group Agents and Social Institutions: Beyond Tuomela’s Social Ontology [PDF]
Tuomela’s work on group agents and social institutionsis very rich and insightful. Although I agree with most of it, two features puzzle me: Tuomela’s ontological individualism, and Tuomela’s stance about constitutive rules. Insofar as ontological individualism is concerned, Tuomela’s claims about group agents seem to support ontological collectivism ...
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Conservation institutions as agents of change [PDF]
Key messages to conservation institutions were drafted during the ICCROM Forum 2013 on Conservation Science so they could, in turn, influence the profession. The first message is a general statement of the fact that conservation science is an essential part of conservation.
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Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
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Taking Chinese non-financial A-share companies listed on the Shenzhen Stock Exchange (SZSE) between 2003 and 2018 as a sample, this paper empirically examines whether and how institutional investors' site visits (SVs) affect corporate investment-cash ...
Jia Liao, Yun Zhan, Yu Yuan
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Changes in Models of Economic Agent and Economic Space
The article analyzes characteristics of homo economicus model and space, where it functions. Principles underlying this quasi-natural scientific model are explained in view of physicalism.
M. Yu. Churilin, T. A. Valiulina
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Agent-based Modeling and Institutional Design [PDF]
The recent economic crisis has led to calls for a comprehensive restructuring of energy, financial, health care, and educational systems. Critics worry that the restructuring of these complex institutional arrangements could produce adverse unintended consequences.
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Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Shifting from formal and institutional to communicative and participatory conceptions of planning does not only alter the understanding of its instruments, but challenges hitherto evaluation techniques with the dilemma of insufficient measurability and ...
Tilman A. Schenk
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