Results 81 to 90 of about 527,927 (245)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

The distant moral agent

Etikk i Praksis: Nordic Journal of Applied Ethics, 2017
Among the defining characteristics of moral cosmopolitanism are the convictions that personal relations, membership in social or political organizations like local communities or nation-states are insignificant for agents when determining their scope of ...
Tom Andreassen
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

LIMITED DELEGATION AND FIRM CONTROL: A PRINCIPAL-AGENT ACCOUNT OF SOUTHERN AFRICAN DEVELOPMENT COMMUNITY (SADC) DECISION-MAKING ON ZIMBABWE’S LAND ISSUE

Journal of International Studies, 2021
This paper accounts for Southern African Development Community (SADC) decision-making on Zimbabwe’s land issue from the year 2000 onwards. Guided by the principal-agent model, this paper argues that the delegation and control dynamics emerging from SADC’
Fungayi Promote Maraire, Mohd. Azizuddin bin Mohd Sani, Siti Darwinda Binti Mohamed Pero   +2 more
doaj  

THE FUTURE OF CUBA UNDER THE ARMED FORCES PERSPECTIVE

Política y Estrategia, 2017
The revolutionary armed forces of Cuba (FAR) are undoubtedly a key agent for the political future of the island, with this fact as a starting point, this article presents an analysis from a theoretical and analytical framework of the military instrument,
MARCO MOLOEZNIK GRUER
doaj   +1 more source

INTERDEPENDENT ARTIFICIAL INSTITUTIONS IN AGENT ENVIRONMENTS

Applied Artificial Intelligence, 2012
In this paper we present a new approach to model artificial institutions AIs that are situated in agent environments where heterogeneous agents reside. An AI is seen here as an entity that can evolve over time, whose rules, in terms of powers, permissions, and obligations, are perceivable as first-class entities by the agents belonging to the ...
Charalampos Tampitsikas, Stefano Bromuri, Nicoletta Fornara, Michael Ignaz Schumacher   +3 more
openaire   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The Influence of Economic and Social Factors on the Choice of Search Procedures Used by Third Party Recruiters

Psychological Topics, 2012
Many organizations employ the services of third party recruiters in order to find suitable candidates for their free positions. Yet, we still know little about what drives search agents to use the specific recruitment tools they use.
Marije de Goede, Ute-Christine Klehe
doaj   +2 more sources