Results 51 to 60 of about 4,850,555 (314)

Human Nature and Institutional Analysis [PDF]

open access: yesSSRN Electronic Journal, 2005
This essay reviews some findings in cognition sciences and examines their consequences for the analysis of institutions. It starts by exploring how humans' specialization in producing knowledge ensures our success in dominating the environment but also changes fast our environment.
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The growth effects of institutional instability

open access: yes, 2012
We study the effects of institutional instability on growth. Using principal components analysis, we construct measures of institutional quality and instability from the political risk index of the International Country Risk Guide.
Christian, Bjørnskov   +3 more
core   +1 more source

Institutional Strategies of Higher Education Institutions and Remuneration Practices for Non-Teaching Staff: A Cluster Analysis of Russian Universities

open access: yesВопросы образования
The authors question the theory-based model of funding distribution in universities, whereby income from scientific activities directly determines scientists' remuneration.
Anastasia E. Sudakova   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Reflexivity and the institutional entrepreneur: a historical exploration [PDF]

open access: yes, 2007
This article sets the idea of the `institutional entrepreneur' in the context of the `autonomous reflexive' as developed in the work of Margaret Archer.
Mutch, A, Alistair Mutch
core   +1 more source

A Polycentric Approach for Addressing Wicked Social Problems

open access: yesAdministrative Sciences
Most social problems are “wicked”, meaning that they are highly complex, intractable, open-ended, and multi-dimensional. In wicked learning environments, information is ambiguous, feedback may be slow, or causes and effects are difficult to ascertain ...
Jordan K. Lofthouse, Leah Kral
doaj   +1 more source

An iterative approach to case study analysis: insights from qualitative analysis of quantitative inconsistencies

open access: yesInternational Journal of the Commons, 2016
Large-N comparative studies have helped common pool resource scholars gain general insights into the factors that influence collective action and governance outcomes.
Allain J Barnett   +11 more
doaj   +1 more source

Institutional Analysis of the Russian Electoral System

open access: yesУправленческое консультирование, 2020
The purpose of this article is an institutional analysis of the factors that hinder the institutionalization of elections in contemporary Russia. Theoretical basis of the study are the behaviorism theory considered in the context of elections, as well as
O. N. Shalashova
doaj   +1 more source

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