Results 141 to 150 of about 4,277,731 (289)

Performance assessment systems for government authorities: from KPI to social impact assessment

open access: yesВекторы благополучия: экономика и социум
The article examines modern approaches to assessing the effectiveness of public authorities in the context of the transformation of the paradigm of public administration. Aim.
Zh.Yu. Kurgaeva
doaj   +1 more source

Workshop series on the role of institutions in East Asian development: Institutional foundations of innovation and competitiveness in East Asia [PDF]

open access: yes
The discussion paper summarizes the results of a workshop that focussed on the institutional foundations of innovation and competitiveness in East Asia.
Pascha, Werner (Ed.)   +2 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

INSTITUTIONAL APPROACH TO DEVELOPMENT OF FUNCTIONAL AND TARGET CONSENT OF SUBJECTS OF HIGHER EDUCATION SYSTEM MODERNIZATION

open access: yesEconomics & Education, 2019
The concept of function and target consent of institutional entities is disclosed as the state and process of interaction between participants in the modernization of the higher education system, which is marked by the presence of mutual interests and ...
Nataliia Kholiavko
doaj  

The Rule of The Jungle in Pakistan: A Case Study on Corruption and Forest Management in Swat [PDF]

open access: yes
Corruption in the forest sector of Swat, Pakistan is impairing the sustainable management of forest. We analyze corruption in a case study setting against the backdrop of the reform options that are most often cited as possible solutions. As we highlight
Lorenzo Pellegrini
core  

Enrich Project Final Report [PDF]

open access: yes, 2010
The Enrich project was a 12 month JISC project funded as part of the Inf11 Programme (2009-11). It was conducted in partnership by the Library, Research and Enterprise and IT Services – with additional technical support from EPrints Services.
Nixon, William
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Economic Activity and Institutions [PDF]

open access: yes
This paper is one of two working papers concerning the waste management sector transition project run from MERIT under the direction of René Kemp.
Saeed Parto
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

ECONOMIC HISTORY — SCIENCE AND ACADEMIC DISCIPLINE On the 5-th anniversary of foundation of the Department „Economic History and History of Economic Thought” Financial University under the Government of the Russian Federation

open access: yesФинансы: теория и практика, 2017
Economic history as a science performs a number of important tasks. It is engaged in the systematization and analysis of factual historical-economic material to justify economic theory, performs a predictive function, which explores the regularities of ...
I. N. Shapkin, N. O. Voskresenskaya
doaj  

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