Results 161 to 170 of about 4,277,731 (289)

Delivering on the promise of competency based medical education - an institutional approach. [PDF]

Can Med Educ J, 2019
Dagnone D, Stockley D, Flynn L, Egan R, van Wylick R, McEwan L, Walker R, Reznick R.   +7 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

INFLUENCE OF A LARGE-SCALE INTERNATIONAL SPORTS EVENT ON THE SOCIAL-ECONOMIC DEVELOPMENT OF A HOST REGION

Russian Journal of Economics and Law, 2012
The article presents a brief summary of examples of social-economic consequences of hosting large-scale international competitions. By the example of Universiade-2013 in Kazan the author shows the influence of a large-scale international sports event on ...
V. A. Leonov
doaj  

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

An Institutional Approach to the Management of Asymptomatic Chorioamnionitis-Exposed Infants Born ≥35 Weeks Gestation. [PDF]

Pediatr Qual Saf, 2019
Chiruvolu A, Petrey B, Stanzo KC, Daoud Y.   +3 more
europepmc   +1 more source

Institutional Approach in Economics and Institutional Economic Thinking

Demagogi: Journal of Social Sciences, Economics and Education
Aspects of economic methodology contained in Institutional economics are often incorporated into orthodox economics. Orthodox economics means economic thoughts that use and continue classical economic views, such as free competition, perfect competition, consumer satisfaction. The person who was most influential and had a dominant role in the existence
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

"Assessing Institutional Efficiency, Growth and Integration" [PDF]

This paper presents a new empirical methodology for evaluation of the institutional system's development in transition economies and the impact it has on economic performance.
Artur Tamazian, Davit Melikyan, Haider A. Khan, Juan Pineiro Chousa   +3 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

An Institutional Approach to Equity and Improvement in Child Health Outcomes. [PDF]

Pediatrics
Unaka N, Kahn RS, Spitznagel T, Henize AW, Carlson D, Michael J, Quinonez E, Anderson J, Beck AF, Cincinnati Children’s Health Equity Network Study Group.   +9 more
europepmc   +1 more source