Results 31 to 40 of about 17,325,720 (353)

Institutional Inertia and Institutional Change in an Expanding Normal-Form Game

open access: yesGames, 2013
We investigate aspects of institutional change in an evolutionary game-theoretic framework, in principle focusing on problems of coordination in groups when new solutions to a problem become available.
Torsten Heinrich, Henning Schwardt
doaj   +1 more source

Institutional change and the development of lagging regions in Europe

open access: yesRegional studies, 2019
This paper assesses whether both the levels and the degree of change in government quality influence regional economic performance in the European Union and, in particular, in its lagging regions.
A. Rodríguez‐Pose, Tobias D. Ketterer
semanticscholar   +1 more source

Entrepreneurial Dynamics and Institutional Changes

open access: yesJournal of Evolutionary Studies in Business-JESB, 2018
Contemporary literature has paid considerable attention to the relationships between formal and informal institutions and early stage firms’ behaviours in different institutional settings in recent years. Given a constantly changing business environment in which companies are operating, there is a need to continuously study how they deal with new ...
Hormiga, Esther   +2 more
openaire   +7 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

The Time is Now to Build a Culture of Wellness in Engineering

open access: yesStudies in Engineering Education, 2021
Prior to the rapid onset of COVID-19, higher education faced a mental health crisis. The COVID-19 outbreak both created and exacerbated stressors for students, with early evidence suggesting that the pandemic has had a significant negative impact on ...
Karin Jensen
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Tunisia’s Institutional Change after the Revolution

open access: yesPolitikon, 2019
The Arab Uprisings started with the Tunisian revolution. These events brought the country to profound change, especially in its institutional asset. Relying on New Institutionalism theory and in particular on the Gradual Change Theory by Mahoney and ...
Luigi Cino
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Donald Trump and Institutional Change Strategies

open access: yesLaws, 2018
This article integrates three fields of study: the “regime politics” paradigm in law and courts, the “institutional change” approach in public policy, and the “unilateral presidency” literature.
Jordan T. Cash, Dave Bridge
doaj   +1 more source

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