Results 121 to 130 of about 648,594 (289)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Complexity and communities: The application of complexity to community studies

, 2015
Understanding community dynamics has always been a challenge for policy-makers. Often community policy has been ineffective and wasteful. This research explores and sets out an alternative, complexity-informed approach to community studies.
Large, David
core  

Vertical and lateral dynamics of middle managers' strategizing for institutional complexity [PDF]

Research suggests that institutional complexity is of strategic importance and recent calls have been made to investigate organizational strategizing in such a situation of multiple institutional logics.
Jonasson, C, Bjerregaard, T
core   +1 more source

Application of the case-mix index and length of stay for hospital waste management comparison: introduction of a new adjusted metric

Frontiers in Public Health
IntroductionHazardous healthcare waste (HHCW) presents escalating environmental and operational challenges, yet traditional indicators such as waste generation rate (kg/bed/day) fail to account for patient complexity or care intensity, leading to biased ...
Adam Kaposi, Attila Nagy, Attila Nagy, Gabriella Gomori, Denes Kocsis   +4 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

The impact of strategic resource seeking and market seeking strategies on foreign entry modes under institutional pressures [PDF]

Multinational corporations (MNCs) are subject to the various dimensions of the external institutional environments where they operate. Institutional theory suggests that MNCs need to conform to the prevailing rules, norms and procedures of the locations ...
Manuel Portugal Ferreira, Fernando A. Ribeiro Serra   +1 more
core  

Static Code Analysis for Identification and Prioritization of Code Quality Remediation in a Resource-Constrained University Academic Information System

Teknika
Software quality directly impacts organizational effectiveness, yet university information systems in developing nations frequently face compounded challenges, including resource constraints, limited developer expertise, and inadequate quality assurance
Muhammad Ridho Kurniawan Pratama, Deni Utama, Rauhil Fahmi, Ali Idrus   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

How do firms respond to institutional complexity under institutional uncertainty?

, 2018
Studies of organizational responses to competing institutional logics generally assume that the dominant or minority positions of competing logics is clear to firms.
Gong, Tianyu
core  

Modeling governance innovation under esg pressure: A DEMATEL–ANP approach to institutional complexity

Journal of Open Innovation: Technology, Market and Complexity
This study introduces a novel, systems-based framework for assessing ESG governance innovation within controversial financial institutions. The research utilizes the Decision-Making Trial and Evaluation Laboratory (DEMATEL) to identify causal ...
Konstantina Ragazou, George Sklavos, Georgia Zournatzidou, Nikolaos Sariannidis   +3 more
doaj   +1 more source