Results 141 to 150 of about 108,282 (303)
This article introduces discourse analysis as a theoretical concept and an empirical methodology that may enable the endogenization of path creation and path breaking changes in conventional models of political path dependencies.
Zschache, Ulrike +4 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Discourse, of Course An overview of research in discourse studies
Discourse, of Course comes after Jan Renkema's Introduction to Discourse Studies (2004) for undergraduates. The new book is a collection of twenty short papers. It is a capita selecta course and meant for graduate programs.
Renkema, Jan.
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The transitions discourse in the ecological modernisation of the Netherlands [PDF]
Discourse analysis, socio-technical transitions, ecological ...
Florian Kern, Adrian Smith
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FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Examining facets of the hegemonic: the globalisation discourse in Greece and Ireland
This paper attempts to make a contribution to the study and understanding of the phenomenon of globalisation and its interplay with national politico-economic systems. How did globalisation resonate and/or dominate in different national contexts?
Antoniades, Andreas
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The Discourse of Professionalism in an Office Memorandum
, 2019 Discourse in the context of the adult EFL Conversation school in Japan have changed as the more severe economic climate and population decline have depleted the numbers of those choosing to engage in English conversation as a hobby activity.
CHIVERS, Leslie +1 more
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