Results 91 to 100 of about 3,072,594 (315)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

INSTITUTIONAL ENVIRONMENT OF FEMALE ENTREPRENEURS IN KAZAKHSTAN

open access: yesХабаршысы. Экономика сериясы, 2018
Positive trend on the number of female entrepreneurs in Kazakhstan has been noticed in recent years. Female entrepreneurs are provided with enormous opportunities in countries with transitional economy including Kazakhstan.
Р. Аман
doaj  

The Institutional Environment and the Banking - Growth Nexus: Theory and Investigation for MENA [PDF]

open access: yes
This paper seeks to provide some theoretical and empirical answers to the following question: Does the institutional environment affect the causality relationship between banking development and economic growth?
Nabi, Mahmoud Sami   +1 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Prerequisites for Forming the Institutional Concept of the National Economy Competitiveness under Conditions of Globalization

open access: yesProblemi Ekonomiki, 2015
The article attempts to prove that under conditions of globalization there have developed objective and subjective prerequisites for forming the institutional concept of the national economy.
Yaremenko Oleh L., Nasyrov Karim Z.
doaj  

Institutions of sustainability in Central and Eastern European Countries [PDF]

open access: yes
The agricultural sector in Central and Eastern Europe (CEE) is confronted by two huge problems simultaneously: transition processes and sustainability. Institutions are very important for both these problems.
Slangen, Louis H.G.   +2 more
core   +1 more source

An institutional perspective on retail internationalization success: Home Depot in Chile [PDF]

open access: yes, 2004
This study utilizes institutional theory to assess the effect of the host institutional environment on the success of internationalizing retailers. According to this framework, retailers succeed in international markets when they adapt their retail ...
Arnold, Stephen, Bianchi, Constanza
core   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Corruption and the Institutional Environment for Growth [PDF]

open access: yes
Several cross-country studies have found that corruption is detrimental to economic growth, but the findings are not universally robust. We utilize the economic freedom index to examine if corruption can facilitate growth by allowing entrepreneurs to ...
Heckelman, Jac C., Powell, Benjamin
core  

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