Results 61 to 70 of about 3,072,594 (315)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Managers’ Short-sightedness, Institutional Environment and Financing Risks

open access: yesInternational Journal of Advanced Business Studies
Managers’ shortsightedness is an important factor affecting the company’s investment decision-making, and the stability of the institutional environment is an important factor affecting managers’ shortsightedness investment management. The article takes
Ruyue Xu, Benjamin Yin Fah Chan
doaj   +1 more source

Enriching a MAS Environment with Institutional Services [PDF]

open access: yes, 2006
Most environments for multi-agent systems limit themselves to providing message transport and white/yellow page services. While these are generic facilities, in some domains other services are necessary, which may map real-world services provided by institutions.
Andreia Malucelli   +2 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Institutional Environments and Mayors’ Role Perceptions

open access: yes, 2017
The role of mayors and their role perception may depend on the changing role of local governments, different national institutional settings, and recruitment patterns. This chapter presents an analysis of the most significant changes among European mayors in terms of their role perceptions over the past decade.
Ivan Koprić   +3 more
openaire   +2 more sources

Local Environment Control and Institutional Crowding-out [PDF]

open access: yes
Regulations that are designed to improve social welfare typically begin with the premise that individuals are purely self-interested. Experimental evidence shows, however, that individuals do not typically behave this way; instead, they tend to strike a ...
Cleve E. Willis   +2 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

ІНСТИТУЦІЙНЕ СЕРЕДОВИЩЕ МУЛЬТИМОДАЛЬНИХ (ЗМІШАНИХ) ПЕРЕВЕЗЕНЬ ЗА УЧАСТЮ ЗАЛІЗНИЧНОГО ТРАНСПОРТУ: ЄС ТА УКРАЇНА

open access: yesInternational Journal of Innovative Technologies in Economy, 2018
The institutional environment of multimodal (mixed) transport with the participation of rail is considered. The analysis of the main provisions of formal institutes regulating multimodal transportations at the international, European and national levels ...
Стасюк О. М.
doaj   +1 more source

Ireland's EU Referendum Experience [PDF]

open access: yes, 2009
The purpose of this article is twofold. First, it surveys Ireland’s European Union referendum experience, tracing the key actors, issues and political dynamics of seven European referendums from 1973 to 2008.
O'Mahony, Jane
core   +1 more source

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