Results 121 to 130 of about 19,856,512 (330)

The Growing Export Performance of Transition Economies: EU Market Access versus Supply Capacity Factors [PDF]

The paper examines the reasons for the remarkable growth of transition economies’ export performance. We distinguish between foreign/EU market access and internal supply capacity factors.
Jože P. Damijan, Maja Ferjančič, Matija Rojec   +2 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Economic performance of exotic dairy cattle under smallholder conditions in the marginal zones of Kenya using three analytical approaches [PDF]

Smallholder exotic dairy cattle have been adopted in the dry marginal zones of Kenya from the high potential areas over the last two decades contrary to the opinion of experts.
Hoag, Dana L., Kavoi, Mutuku Muendo, Pritchett, James G.   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Institutional factors associated with early mortality of newly diagnosed acute promyelocytic leukemia. [PDF]

Blood Cancer J, 2022
Matsuda K, Jo T, Matsui H, Fushimi K, Yasunaga H, Sugimoto K.   +5 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Investigating the Reasons for the Difference in Total Factor Productivity Between East and West Asia with Emphasis on Institutions, Human Capital and Relative Backwardness

برنامه‌ریزی و بودجه, 2022
The trend of total factor productivity (TFP) and GDP growth per capita in most East Asian countries is upward and in most West Asian countries is downward or fluctuating.
Saeid Jafari, Marziyeh Esfandiari, Mosayeb Pahlavani   +2 more
doaj  

What drives patients' acceptance of Digital Therapeutics? Establishing a new framework to measure the interplay between rational and institutional factors. [PDF]

BMC Health Serv Res, 2023
Carrera A, Zoccarato F, Mazzeo M, Lettieri E, Toletti G, Bertoli S, Castelnuovo G, Fresa E.   +7 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Chinese multinationals: how do institutional factors affect their location patterns?

Management Letters/Cuadernos de Gestión, 2011
This paper analyses the impact of various host country institutional factors on the location patterns of 29 large Chinese multinationals. From a sample of 127 outward foreign direct investment (FDI) decisions made in 52 countries, our findings suggest ...
Diego Quer Ramón, Enrique Claver Cortés, Laura Rienda García   +2 more
doaj