Results 21 to 30 of about 17,141,363 (254)
The Nature of Social Fact in B. Epstein’s Social Ontology
RUDN Journal of Philosophy, 2022 The research analyzes the social ontology of the American philosopher B. Epstein. Social ontology studies the nature of the social world: what are its main elements and how they come together.
Svetlana I. Platonova
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
CríticaThis paper presents three objections to Marco Ruffino’s account of contingent a priori truths. First, I argue that Ruffino’s “Philonous’ Objection” neglects what is widely considered the mark of perception—namely, perceptual constancies, which allow ...
Emiliano Boccardi
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Human Social Reality and Language
Phenomenology and Mind, 2016 My question, in this work, will be: How do human beings create such complex phenomena as money, government, property, and marriage? Here, I will maintain four theses.
John R. Searle
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Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Social Ontology and Immanent Realism
Phenomenology and Mind, 2016 What are the intentional objects of groups’ beliefs? This paper claims that they are immanent facts, i.e., facts which exist only within groups’ minds. Since in relevant literature the notion of immanent object and the related theory of “immanent realism”
Alessandro Salice
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Les limites de la performativité des énoncés en économie. Les apports de John Searle
Œconomia, 2011 The problematic of performativity has recently fostered numerous criticisms and debates about the status of the economic discourse. Indeed the affirmation that the economist shapes the world by describing it could lead to the subjectivist idea that each ...
Nicolas Brisset
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
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