Results 101 to 110 of about 711,360 (309)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Comparative analysis of research quantity, quality, and impact in MENA research centers

open access: yesLibyan Journal of Medicine
Research performance in the Middle East and North Africa (MENA) is often assessed using national aggregates that mask substantial institutional variation.
Amin Bredan
doaj   +1 more source

COPYRIGHTS, COMPETITION AND DEVELOPMENT: THE CASE OF THE MUSIC INDUSTRY [PDF]

open access: yes
The economic importance of copyright industries in developed market economies has been well documented. Although less important in developing countries, this is likely to change with the growing weight of the service sector in these economies and its ...
B. ANDERSEN,   +2 more
core  

Corporate governance, moral hazard and conflict of interest in Italian universal banking, 1914-1933 [PDF]

open access: yes, 2003
Universal banking is widely held to enjoy comparative advantages in corporate finance. Recent theories of financial intermediation argue that 'insider systems' are better suited to effectively deal with long-term growth and moral hazard problems. However,
Battilossi, Stefano
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Toward the elaboration of a Universal Design Protocol in the National University of Córdoba

open access: yesRevista de Urbanismo, 2014
This article is aimed at expressing the main aspects of the process of administration of an Urban and Building Protocol of Accessibility based on the principles of Universal Design in the National University of Cordoba in Argentina.The main concepts that
Mauricio Alexei Mareño Sempertegui   +2 more
doaj   +1 more source

The rise of independent administrative authorities in Turkey: A close look on sources, successes and challenges of this new institutional transformation [PDF]

open access: yes
Turkey has experienced important institutional transformation during the last decades. In particular, it has started with liberal policies of early 1980s.
Göktaylar, Yavuz
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Traceability System Model for Quality Gelatin Raw Material of Cattle Hides

open access: yesAnimal Production: Indonesian Journal of Animal Production, 2010
Several criteria must be accomplished within the provision of quality products in terms of the types of materials, the processing methods and effort to get it.
S Nur, EG Sa'id, JM Munandar, Machfud
doaj  

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