The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu +7 more
wiley +1 more source
Trauma Activation Fee Variations Across Hospital Ownership, Safety-net, American College of Surgeons Committee-on-Trauma Verification, and State Designation Status. [PDF]
Cho NY +8 more
europepmc +1 more source
Do Firms Benefit from Institutional Cross-Ownership? Evidence from Chinese Overseas Investments
Baizhou Lu +3 more
openalex +1 more source
Corporate Governance, Ownership Structures and IT Investments. An Institutional approach.
Nestor U. Salcedo +2 more
openalex +1 more source
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan +16 more
wiley +1 more source
Determinants of domestic violence against women in Cambodia: How digital access, media exposure, motorcycle ownership, and partners' alcohol use matter. [PDF]
Um S +5 more
europepmc +1 more source
Institutional Ownership and Stock Liquidity: Evidence From an Emerging Market [PDF]
Ngoc Bao Dinh, Van Nguyen Hong Tran
openalex +1 more source
A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi +8 more
wiley +1 more source
Mobile Health Technology Ownership and Use Among Cancer Survivors in a Health System. [PDF]
Wang SD +9 more
europepmc +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source

