Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Institutions are the fundamental determinants of economic growth. Therefore, a high institutional quality of among the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTPP) countries will be important to ensure continuing economic
C.Y. Chong, Chong, Choy Yoke
core +1 more source
Institutional design matters: institutional causes of the Brazilian wine industry’s poor performance
Triple Helix theory prescribes coordinated actions among government, research institutions and industry to achieve growth. However, the Brazilian wine industry case shows that simply having the institutions is not enough – the institutional framework ...
Daniel D. Guedes, Andy Hira
doaj +1 more source
Improving Compliance With Institutional Performance on Train of Four Monitoring. [PDF]
Santapuram P +9 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Public officials and their institutional environment - an analytical model for assessing the impact of institutional change on public sector performance [PDF]
To perform well, public officials must be confident enough about the future, to be able to see a relationship between their efforts, and an eventual outcome. Their expectations are shaped by their institutional environment. If the rules are not credible,
Manning, Nick +2 more
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Examining the moderating role of institutional leadership in the relationship between institutional pressures and the use of performance measurement systems: Evidence from local government in Yogyakarta, Indonesia [PDF]
Type of the article: Research Article AbstractInstitutional leadership represents an important internal capacity for institutionalizing performance measurement systems within local government, particularly in contexts where external forces such as ...
Anthonius H. Citra Wijaya, Rusdi Akbar
doaj +1 more source
Perceptions of institutional performance and compliance to non-pharmaceutical interventions: How performance perceptions and policy compliance affect public health in a decentralized health system. [PDF]
Paschoalotto MAC +8 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Governmental Context Determines Institutional Value: Independently Certified Performance and Failure in the Spanish Newspaper Industry. [PDF]
Many societies demand that independent professionals (e.g. auditors) certify the performance of firms. The value placed on such certification (i.e. the public perception of reliability/unreliability that may impact on an organization's success/failure ...
Núñez-Nickel, Manuel +2 more
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