Results 81 to 90 of about 1,810,262 (303)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Nonlinear impact of institutional quality on economic performance within the comprehensive and progressive agreement for trans-pacific partnership

open access: yes, 2020
Institutions are the fundamental determinants of economic growth. Therefore, a high institutional quality of among the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CPTPP) countries will be important to ensure continuing economic
C.Y. Chong, Chong, Choy Yoke
core   +1 more source

Institutional design matters: institutional causes of the Brazilian wine industry’s poor performance

open access: yesPrometheus, 2013
Triple Helix theory prescribes coordinated actions among government, research institutions and industry to achieve growth. However, the Brazilian wine industry case shows that simply having the institutions is not enough – the institutional framework ...
Daniel D. Guedes, Andy Hira
doaj   +1 more source

Improving Compliance With Institutional Performance on Train of Four Monitoring. [PDF]

open access: yesJ Educ Perioper Med, 2023
Santapuram P   +9 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Public officials and their institutional environment - an analytical model for assessing the impact of institutional change on public sector performance [PDF]

open access: yes
To perform well, public officials must be confident enough about the future, to be able to see a relationship between their efforts, and an eventual outcome. Their expectations are shaped by their institutional environment. If the rules are not credible,
Manning, Nick   +2 more
core  

Examining the moderating role of institutional leadership in the relationship between institutional pressures and the use of performance measurement systems: Evidence from local government in Yogyakarta, Indonesia [PDF]

open access: yesProblems and Perspectives in Management
Type of the article: Research Article AbstractInstitutional leadership represents an important internal capacity for institutionalizing performance measurement systems within local government, particularly in contexts where external forces such as ...
Anthonius H. Citra Wijaya, Rusdi Akbar
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Governmental Context Determines Institutional Value: Independently Certified Performance and Failure in the Spanish Newspaper Industry. [PDF]

open access: yes
Many societies demand that independent professionals (e.g. auditors) certify the performance of firms. The value placed on such certification (i.e. the public perception of reliability/unreliability that may impact on an organization's success/failure ...
Núñez-Nickel, Manuel   +2 more
core  

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