Results 71 to 80 of about 2,242,644 (337)

Drivers toward Social Entrepreneurs Engagement in Poland: An Institutional Approach

open access: yesAdministrative Sciences, 2020
The aim of this study is to identify the factors that influence the involvement of individuals in social entrepreneurship in Poland from an institutional economics perspective.
Agnieszka Pacut
doaj   +1 more source

Institutional Framework and Poverty: A Transition Economy Perspective [PDF]

open access: yes
Institutions, Poverty reduction ...
Ahsan, Syed M.
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The Function of a Medical Director in Healthcare Institutions: A Master or a Servant

open access: yesHealth Services Insights, 2013
The function of a medical director is presented along with features of efficiency and deficiencies from the perspective of healthcare system improvement.
Antoine Kossaify   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Dropout from secondary education: All's well that begins well [PDF]

open access: yes
Despite the increased attention to students leaving secondary education without a diploma, numerous students dropout yearly. This paper makes a distinction between the 'individual perspective' and the 'institutional perspective' of dropping out.
De Witte, K.
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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