Results 301 to 310 of about 740,226 (329)

Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation

Clinical Anatomy, EarlyView.
ABSTRACT Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs).
Lily Mae Miller, Peter Douglas, Julie Glen, Emma Aitken   +3 more
wiley   +1 more source

Stepping up to the moment: collaborating on a data management and sharing workshop series. [PDF]

J Med Libr Assoc
Samuel SM, Sevryugina YV, MacEachern M, Saylor K, Woodbrook R.   +4 more
europepmc   +1 more source

CD24 is a promising immunotherapeutic target for enhancing efficacy of third‐generation EGFR‐TKIs on EGFR‐mutated lung cancer

Cancer Communications, EarlyView.
Abstract Background Third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) show initial efficacy in EGFR‐mutated lung cancer, but residual disease persists. This study aimed to investigate cluster of differentiation 24 (CD24) as a translational immunotherapeutic target for enhancing third‐generation EGFR‐TKI efficacy.
Jiaqi Liang, Guoshu Bi, Xiaolong Huang, Zhijie Xu, Yiwei Huang, Yunyi Bian, Guangyao Shan, Wei Guo, Yuanliang Yan, Qihai Sui, Xiaodong Yang, Zhencong Chen, Tao Lu, Huan Zhang, Qun Wang, Wei Jiang, Cheng Zhan   +16 more
wiley   +1 more source

Computed ECD spectral data for over 10,000 chiral organic small molecules. [PDF]

Sci Data
Long D, Li Z, Xu X, Liu C, Zhang H, Cao X, Yang L, Wang X, Mo F.   +8 more
europepmc   +1 more source

A Brief Primer on Institutional Repositories

Against the Grain, 2012
openaire   +4 more sources

Potent Antisickling Furaldehyde Analogs for Acute Sickle Cell Therapy: Enhanced Efficacy and Intravenous Formulation Potential

ChemMedChem, EarlyView.
This study reports novel 5‐HMF analogs with potent antisickling activities. Lead compound MMA509 enhances hemoglobin oxygen affinity and prevents erythrocyte sickling. Crystal structure of hemoglobin‐MMA509 complex explains MMA509 mechanism of action. An IV formulation is successfully developed, positioning MMA509 as a promising fast‐acting treatment ...
Abdelsattar M. Omar, Moustafa E. El‐Araby, Tarek A. Ahmed, Akua K. Donkor, Albert Opare, Mohini S. Ghatge, Anfal S. Aljahdali, Rana T. Alhashimi, Trevohn N. Robinson, Benita Balogun, Mariana Macias, Salma Roland, Yan Zhang, Faik N. Musayev, Osheiza Abdulmalik, Martin K. Safo   +15 more
wiley   +1 more source

Advancing image-based meta-analysis through systematic use of crowdsourced NeuroVault data. [PDF]

Sci Rep
Peraza JA, Kent JD, Blair RW, Poline JB, Nichols TE, de la Vega A, Laird AR.   +6 more
europepmc   +1 more source

Electronic Patient File‐Embedded Model‐Informed Precision Dosing Compared with Physician Dosing of Tacrolimus in Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers, Pieter Annaert, Borefore Jallah, Maarten Naesens, Maxine Teuns, Annouschka Laenen, Ruben Faelens   +6 more
wiley   +1 more source

Bulk RNA-seq of skeletal muscle reveals the role of ZBED6 in sepsis-induced muscle atrophy in minipigs. [PDF]

Sci Data
Liu H, Shi W, Zheng Y, Yang S, Wang Y, Yang M, Yang Z, Mao E, Shang H, Chen E, Chen Y.   +10 more
europepmc   +1 more source

Red cell distribution width (RDW) is independently associated with all-cause mortality in adult patients with osteomyelitis admitted to the intensive care unit. [PDF]

PLoS One
Liang L, Chen Z, He Z, Tao H, Chen Y, Liu T.   +5 more
europepmc   +1 more source