Results 101 to 110 of about 5,345,635 (309)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Institutional Groundings for Transformative Work with Students and in Schools
Educação em Foco, 2016 Despite local, state and federal funding for compulsory education, educational opportunity is not evenly distributed in the United States. A range of challenges disproportionately face students of color and the poor and lead to uneven achievement ...
Kevin Michael Foster
doaj +1 more source
Executive Summary of Work Package 3 on Availability and Choice of Care of the ANCIEN Project. ENEPRI Research Report No. 101, February 2012 [PDF]
, 2012 Work Package 3 on the Availability and Choice of Care of the ANCIEN project aims to document the forces driving the choice of formal and informal care across European countries and to characterise the linkages between the type of care used by dependent ...
Jiminez-Martin, Sergi +2 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Role of institutions for effective telecommunications regulation: Palestine as a case study [PDF]
This paper investigates Palestine's institutional foundations in order to decide on the most appropriate telecommunications regulatory system. It is based on the work of Levy and Spiller's institutional endowment framework.
Dhaher, Omar
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Scholarly Communications Report on Activities 2015-16
, 2016 2015-16 annual report for Scholarly Communications work at Musselman Library, including Gettysburg College\u27s institutional repository, The Cupola: Scholarship at Gettysburg College.
Wertzberger, Janelle L.
core
Discourse revisited : dimensions and employment of first-order strategy discourse during institutional adoption [PDF]
Despite decades of research on strategy, we still know little about what the concept of strategy means to actual strategists and how they use it in practice.
Barry D +12 more
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source