Results 51 to 60 of about 5,345,635 (309)

Strengthening the World Trade Organization – Critical Demands for Imperative Success: Identifying Politically Viable Options for Incremental Reform [PDF]

open access: yes, 2018
The multilateral trade regime and the World Trade Organization (WTO) are a major success story of global governance. In few other domains have states managed to cooperate as successfully in the last 70 years as in global trade affairs.
Basedow, Robert
core  

Performative Work: Bridging Performativity and Institutional Theory in the Responsible Investment Field [PDF]

open access: yes, 2018
Callon’s performativity thesis has illuminated how economic theories and calculative devices shape markets, but has been challenged for its neglect of the organizational, institutional and political context.
Akrich M.   +79 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Making aid work: institutional thresholds and FDI [PDF]

open access: yesApplied Economic Analysis
Purpose – The purpose of this paper is to analyse the institutional threshold effects of foreign aid on foreign direct investment (FDI). Design/methodology/approach – This paper develops a theoretical model from an extended Solow model that introduces ...
Dongni Wang, Carmen Fillat-Castejón
doaj   +1 more source

Tutoring Translingual Writers: The Logistics of Error and Ingenuity [PDF]

open access: yes, 2017
The writing center is perfectly positioned to take the lead in institutional responses to the exigencies of translingualism. Translingual writers—writers who move with variable facility between linguistic and rhetorical expression in two or more ...
Newman, Mendez Beatrice
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Building institutional capacity for industrial symbiosis development : a case study of an industrial symbiosis coordination network in China [PDF]

open access: yes, 2016
Recent research has examined how the concept of institutional capacity relates to the ability of organisations to deliver industrial symbiosis, and in particular how that ability itself can develop over time.
Chen, Yong   +2 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

The role of the research sector in ABS governance [PDF]

open access: yes, 2007
The aims of this paper are to examine the renewed role of the academic sector in the innovation chain, starting from traditional knowledge and wild genetic resources and ending with a final product marketed by bio-industries; to identify changes in the ...
Brahy, Nicolas, Louafi, Selim
core  

Home - About - Disclaimer - Privacy