Results 221 to 230 of about 58,709,063 (261)

TREATMENT OF GASTRIC CANCER ACCORDING TO THE COMPLEXITY OF THE HOSPITAL ONCOLOGY UNIT: ANALYSIS OF 33,774 PATIENTS OVER TWO DECADES. [PDF]

Arq Bras Cir Dig
Ramos MFKP, Pereira MA, Luizaga CTM, Lombardo V, Leite VB, Peres SV, Pinheiro RN, Ribeiro Junior U.   +7 more
europepmc   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

Microbiota-immune dysregulation in cervical cancer patients from Western Mexico: linking gut dysbiosis and NK cell exhaustion as promising biomarkers. [PDF]

Front Immunol
Klimov-Kravtchenko K, Baltazar-Díaz TA, Haramati J, Castaño-Jiménez PA, Solorzano-Ibarra F, Rojas-Diaz JM, Garcia-Barrientos NT, Cruz-Ramos JA, Facundo-Medina CG, Del Toro-Arreola S, Bueno-Topete MR.   +10 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Opportunities for promoting open data in the Caribbean through biobanks. [PDF]

Rev Panam Salud Publica
Saluja S, Anderson SG.
europepmc   +1 more source

The Fertility Reduction Effects of the Colorado Family Planning Initiative by Age and Parity

Health Economics, EarlyView.
ABSTRACT We use restricted‐access birth records from the National Vital Statistics System (NVSS) to document the full age and parity fertility effects of the Colorado Family Planning Initiative (CFPI). The CFPI provided access to every FDA approved method of contraception for free to anyone living below approximately 200% of the federal poverty line ...
James Flynn, Amanda Stevenson, Sara Yeatman, Katie Genadek, Jane Menken, Stefanie Mollborn, Leslie Root   +6 more
wiley   +1 more source

Mejorar la comunicación sobre la equidad en la salud en la investigación observacional (STROBE Equidad): la lista de verificación ampliada y su elaboración. [PDF]

Rev Panam Salud Publica
Dewidar O, Shamseer L, Melendez-Torres GJ, Akl EA, Ramke J, Wang X, Oloyede O, Young T, Nicholls SG, Marshall Z, Kennedy M, Hardy BJ, Rizvi A, Ghogomu E, Rader T, Waddington HS, Shea B, Nguilefem MN, Ellingwood H, Wolfenden L, Tufte J, Horsley T, Pottie K, Cuervo LG, Juando-Prats C, Feng C, Sharp MK, Little J, Owusu-Addo E, Francis D, Kredo T, Mahande MJ, Chamberlain C, Pantoja T, von Elm E, Bhutta ZA, Tugwell P, Wiysonge CS, Funnell S, Jull J, Mbuagbaw L, Welch V.   +41 more
europepmc   +1 more source

Health System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney, Iván Lyra González, Mauricio Cuello, Mariél de Aquino Goulart, Alex D. McMahon, Claire Paterson, James McCaul, Maja Popovic, Lorenzo Richiardi, Silvia Lopez de Blanc, Maria Paula Curado, Marta Vilensky, HEADSpAcE Consortium, Elmira Ebrahimi, Apiwat Sangphukieo, Hanla A Park, Valerie Gaborieau, Wolfgang Ahrens, Laia Alemany, Lidia MRB Arantes, Jaroslav Betka, Cristina Canova, David I Conway, Mauricio Cuello, Maria Paula Curado, Ana Carolina de Carvalho, Jose Carlos de Oliviera, Mark Gormley, Maryam Hadji, Claire M Healy, Ivana Holcatova, Luis P Kowalski, Pagona Lagiou, Areti Lagiou, Gary J Macfarlane, Sandra Perdomo, Luis Felipe Ribiero Pinto, Jose Roberto V Podesta, Jerry Polesel, Miranda Pring, Hamideh Rashidian, Ricardo R Gama, Lorenzo Richiardi, Max Robinson, Paula A Rodriguez‐Urrego, Sheila C Soares‐Lima, Nicolas Timpson, Marta Vilensky, Sandra V von Zeidler, Tim Waterboer, Kazem Zendehdel, Ariana Znaor, Paul Brennan, James McKay, Shama Virani, Tom Dudding, Roque Adam, Antonio Agudo, Shaymaa F AlWaheidi, Miquel Angel Pavon, Namrah Anwar, Paola Engelmann Arantes, Lisa Arguello, Yubelly Avello, Lucas Avondet, Ana M Baldión‐Elorza, Camila Batista Daniel, Bianca Beraldi, Barbara Berenstein, Patricia Bernal, Natália Bernardino Rodrigues, Josipa Bilic Zimmermann, Marianna G Botta, Jesús Brenes, Nicole Brenner, Carol Brentisci, Catalina Burtica, María L Cabañas, Erick Cantor, Raiany S Carvalho, Andre L Carvalho, Luigi Chiusa, Priscilia Chopard, Qurratulain Chundriger, Omar Clavero, Isabela Costa, Grant Creaney, Cecilia Cuffini, Tauana C Dias, Evandro Duccini de Souza, Lais C Durant, Alberto Escallón, Gisele Aparecida Fernandes, Béatrice Fervers, Valentina Fiano, Frederico Firme Figueira, Regina Furbino Villefort, Manuela Gangemi, Paolo Garzino‐Demo, Mahin Gholipour, Raul Giglio, Mariel A Goulart, Jéssica Graça Sant'Anna, Marek Grega, Anna Clara Gregório Có, Arnau Guasch, Jose A Hakim, David N Hayes, Marco Homero de Sá Santos, Katrina Hurley, Magalí Insfran, Giuseppe C Iorio, Moghira Iqbaluddin Siddiqui, Jannik Johannsen, Martin Kaňa, Jens Peter Klussmann, Evelio Legal, Jeferson Lenzi, Fernando Luiz Dias, Iván Lyra González, Willene Machado Zorzaneli, Ricardo Mai Rocha, Manel Mañós, Priscila Marinho de Abreu, Maryam Marzban, James McCaul, Alex D. McMahon, Carlos Mena, Elismauro F Mendonça, Laura Mendoza, Lorena Meza, Birgitta Michels, Matinair S Mineiro, Chiara Moccia, Pamela Mongelos, Ana L Montealegre‐Páez, Francisca Morey Cortes, Alvaro Muñoz, Andy Ness, Aline B Neves, Marco Oliva, José Carlos de Oliveira, Hernán Ortiz, José Ortiz, Marta Osorio, Vanessa Ospina, Oliviero Ostellino, Mauricio Palau, Claire Paterson, Sonia Paytubi Casabona, Giancarlo Pecorari, David M Pereira, Olivia Pérol, Shahid Pervez, Alicia Pomata, Maja Popovic, Alisson Poveda, Carol P Prado, Kristina M Prager, Guglielmo Ramieri, Juliana NI Rego, Rui M Reis, Helene Renard, Umberto Ricardi, Giuseppe Riva, Frederic Rodilla, Ingrid Rodriguez, María I Rodríguez, Alastair Ross, Pierre‐Eric Roux, Tazeen Saeed Ali, Pierre Saintigny, Juan J Santivañez, Cristóvam Scapultampo‐Neto, Javier Segovia, Agenor Sena, Ricardo Serrano, Shachi J Sharma, Oliver Siefer, Stephanie Smart, Bruna P Sorroche, Cinthia Sosa, Juliana Souza de Oliveira, Antonella Stura, Steven Thomas, Oscar Torres, Sara Tous, Gonzálo Ucross, Adriana Valenzuela, José Roberto Vasconcelos de Podestá, Alex Whitmarsh, Sylvia Wright, Shaymaa Alwaheidi, Paul Brennan, Shama Virani, Al Ross, David I Conway   +196 more
wiley   +1 more source

Naringin and Naringenin in Liver Health: A Review of Molecular and Epigenetic Mechanisms and Emerging Therapeutic Strategies. [PDF]

Antioxidants (Basel)
Flores-Peña R, Monroy-Ramirez HC, Caloca-Camarena F, Arceo-Orozco S, Salto-Sevilla JA, Galicia-Moreno M, Armendariz-Borunda J.   +6 more
europepmc   +1 more source

Pattern of Progression of Oral Potentially Malignant Disorders From Real‐World Data: A 24‐Year Study

Head &Neck, EarlyView.
ABSTRACT Background Oral potentially malignant disorder (OPMD) prognostication is limited by uncertainty of which lesions will progress and the aggressiveness of lesion progression. We defined patterns and kinetics of progression in a large cohort of OPMD subjected to serial clinical and histologic examinations. Methods This 24‐year study evaluated the
Subin Surendran, Sumsum P. Sunny, Preethi M. Chathoth, William J. Magner, S. Lynn Sigurdson, Mihai Merzianu, Norbert Sule, Anurag K. Singh, Kimberly E. Wooten, Ryan P. McSpadden, Vishal Gupta, Amritha Suresh, Ashok Z. Samuel, Rohit Bhargava, Praveen N. Birur, Wesley L. Hicks Jr, Moni Abraham Kuriakose   +16 more
wiley   +1 more source