Results 271 to 280 of about 6,791 (285)

Impacto econômico da incorporação de biossimilares em um instituto do câncer de um hospital filantrópico

Maria Luísa BRODT-LEMES, Diana Saiara BRUSCATO, Douglas Silva MADRUGA, Joice SMANIOTTO, Julia Roberta SAGGIORATO-LUBIAN, Letícia Tramontina DE-VILLA, Suhélen Caon, Thamyrys Bessa SILVA   +7 more
openalex   +1 more source

Comparative Analysis of Circulating and Synovial Immune Cells in Early Untreated Rheumatoid Arthritis and Their Relationship With Molecular Pathology and Disease Outcomes

Arthritis &Rheumatology, EarlyView.
Objective To assess the relationship of circulating and synovial immune cells with synovial molecular pathology and disease outcomes in patients with early rheumatoid arthritis (RA). Methods Patients with early (<12 months) treatment‐naive RA (n = 144) from the Pathobiology of Early Arthritis Cohort were included in this post hoc analysis.
Felice Rivellese, Elena Pontarini, Liliane Fossati‐Jimack, Rita A. Moura, Vasco C. Romão, João Eurico Fonseca, Alessandra Nerviani, Cankut Çubuk, Katriona Goldmann, Giovanni Giorli, Myles Lewis, Michele Bombardieri, Costantino Pitzalis, on behalf of the Pathobiology of Early Arthritis Cohort (PEAC) investigators   +13 more
wiley   +1 more source

AVALIAÇÃO ODONTOLÓGICA ANTES DO TRANSPLANTE DE CÉLULAS-TRONCO HEMATOPOIÉTICAS NO INSTITUTO NACIONAL DE CÂNCER

LDB Alves, SP Lermontov, JKP Queiroz, JSR Pereira, ACDS Menezes, S. Bento Pereira, MCR Moreira, Décio Lerner, Henrique dos Santos Antunes   +8 more
openalex   +1 more source

The feasibility of pharmacokinetic‐based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Pharmacokinetic (PK)‐guided dosing of hydroxyurea for children with sickle cell anaemia (SCA) could optimize dosing and improve outcomes, but its feasibility has not been demonstrated in low‐resource settings where the majority of affected children live.
Alexandra Power‐Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Sadat Aliwuya, Kathryn McElhinney, Andrea L. Conroy, Adam Lane, Chandy John, Alexander A. Vinks, Teresa Latham, Robert O. Opoka, Russell E. Ware   +13 more
wiley   +1 more source

[Estimates of mortality from external causes in Brazil, 2010-2019: methodology for redistribution of garbage causes]. [PDF]

Cad Saude Publica
Soares Filho AM, Teixeira RA, Dantas Junior AB, Souza JB, Montenegro MMS, Vasconcelos AMN, Souza MFM, França EB, Malta DC.   +8 more
europepmc   +1 more source

Intricate Regulation of Sphingolipid Biosynthesis: An In‐Depth Look Into ORMDL‐Mediated Regulation of Serine Palmitoyltransferase

BioEssays, EarlyView.
Multiple enzymes play a crucial role in regulating the biosynthesis of de novo sphingolipids. This regulation starts with the rate‐limiting enzyme, serine palmitoyltransferase (SPT), which catalyzes the first step of the pathway. Disruptions in this regulatory process can lead to serious diseases.
Usha Mahawar, Binks Wattenberg
wiley   +1 more source

Factorial structure of quality of life, satisfaction with caregiving and caregiver burden in palliative care: A systematic review. [PDF]

Nurs Open
Llop-Medina L, Ródenas-Rigla F, Gallego-Valadés A, Garcés-Ferrer J.   +3 more
europepmc   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)

Chemistry &Biodiversity, EarlyView.
This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni, Milena Costa Bassicheto, Maria Vitória de Oliveira, Ana Beatriz dos Santos de Souza, Gabriella Melo Alves, Thiago André Moura Veiga   +5 more
wiley   +1 more source