Results 281 to 290 of about 517,391 (323)
Psychiatric Comorbidities and Treatment Modalities in Children With Osteogenesis Imperfecta: A Systematic Review of Mental Health
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT
To evaluate the prevalence of psychiatric signs and symptoms and describe psychotherapeutic and psychopharmacological interventions among children with osteogenesis imperfecta (OI). PRISMA guidelines were followed, and the study was registered in PROSPERO (CRD42024588284). Studies (n = 1419) were identified across five databases.Julia M. Morales, Camille F. Villar, Beatriz Varman, Gianna M. Colombo, Danqi Li, Sarah J. Sadek, Marie‐Eve Robinson, Chaya N. Murali, Kara Ayers, Jocelyn Gomez, Brendan Lee, V. Reid Sutton, Eric A. Storch, Andrew D. Wiese +13 morewiley +1 more sourceSinonasal Sarcomas Management: An International Consensus Statement
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Introduction
Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.Alessandro Vinciguerra, Francesca Caspani, Marco Valentini, Anna Maria Camarda, Salvatore Provenzano, Eric W. Wang, Cem Meço, Marco Ferrari, Pavol Surda, Semi Harrabi, Fernando Augusto Batista Campos, Javier Martin Broto, B. Ashleigh Guadagnolo, Pierina Navarria, Ali Hosni, Nadia Hindi, Antoine Italiano, Daniel M. Trifiletti, Bernd Kasper, Benjamin Verillaud, Alberto Schreiber, Paolo Castelnuovo, Piero Nicolai, Iacopo Dallan, Matias Chacon, Shirley Y. Su, Juliette Thariat, Claudia Valverde, Matt Lechner, Jean Yves Blay, Maria Rosaria Fiore, Jean Anderson Eloy, Mehdi Brahmi, James N. Palmer, Victor Castro Oliden, Daniela Greto, Iwona Lugowska, Angelo Paolo Dei Tos, Thibaut van Zele, Alkis J. Psaltis, Paolo Giovanni Casali, Armelle Dufresne, Claudia Sangalli, Christos Georgalas, Ester Orlandi, Peter‐John Wormald, Philippe Herman, Ricardo Carrau, Ehab Y. Hanna, Lisa Licitra, Mario Turri‐Zanoni, Paolo Battaglia +51 morewiley +1 more sourceMechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background
Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee +8 morewiley +1 more sourceTri‐Modal Anticancer Strategies with Doxorubicin‐Loaded Iron Oxide Nanoparticles Integrating Chemo and Magneto‐Photothermal Therapeutic Effects
Advanced NanoBiomed Research, EarlyView.Maghemite nanoparticles functionalized with doxorubicin enable synergistic chemo‐magneto‐photothermal therapy. Combining pH‐sensitive drug release with localized heating at clinically relevant low doses enhances tumor cell death while minimizing toxicity.Rosalía López‐Méndez, Nuria Lafuente‐Gómez, Eva Céspedes, Mónica Dhanjani, Marina París‐Ogáyar, Francisco José Terán, Aida Serrano, Julio Camarero, Gorka Salas, Claire Wilhelm, Álvaro Somoza, Ana Espinosa +11 morewiley +1 more source