Results 121 to 130 of about 2,457,499 (300)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Periodic Single-Pass Instruction Sequences [PDF]

open access: yes, 2013
A program is a finite piece of data that produces a (possibly infinite) sequence of primitive instructions. From scratch we develop a linear notation for sequential, imperative programs, using a familiar class of primitive instructions and so-called ...
Bergstra, Jan A., Ponse, Alban
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A performance comparison of several superscalar processsor [sic] models with a VLIW processor [PDF]

open access: yes, 1992
Superscalar and VLIW processors can both execute multiple instructions each cycle. Each employs a different instruction scheduling method to achieve multiple instruction execution.
Bagherzadeh, Nader, Lenell, John
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

When the world grows smaller: Renewing instruction methods for international students [PDF]

open access: yes, 2010
Please note: This is a conference proceeding from an interactive session at the 2008 LOEX Conference. Abstract: With globalization diversifying our university culture, American universities are welcoming an increasing population of international students.
Hensley, Merinda Kaye
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Instructions And Instruction Set

open access: yes, 2022
Dawoud Shenouda Dawoud, R. Peplow
openaire   +1 more source

Instructions and Instructed Actions

open access: yes, 2019
Se realiza la traducción del Capítulo Seis de El Programa de la Etbometodología por Harold Garfinkel.
Garfinkel, Harold   +2 more
openaire   +1 more source

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