Results 121 to 130 of about 903,001 (251)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Kansas Schools, Vol. 15 [1958-1959]
, 1958 Publication information Monthly during school yearEducational Survey Is Underway Education Bill To Aid Kansas Sub-committees Prove Helpful Elect Mrs. Jones Several SDofE Staff Changes Children Choose Author Honor to Agnes Engstrand Two Kansas School Men ...
Kansas State Department of Public Instruction
core
Effectiveness of Course-Integrated and Repeated Library Instruction on Library Skills of Education Students [PDF]
, 2003 Given the investment in librarian time and energy and faculty and student time constraints, it was deemed important to assess effectiveness of course-integrated library instruction, and more specifically, whether repeated library instruction has a ...
Beile, Penny, Penny M. Beile
core +1 more source
The Egyptian Journal of Internal MedicineBackground Diabetic ketoacidosis (DKA) is a serious, life-threatening condition known for its profound hydro electrolytic disturbances and multiple complications, including cerebral edema and circulatory collapse. While this complication is traditionally
Abderrahmane Bouchaala +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Kansas Schools, Vol. 18 [1961-1962]
, 1961 Publication information Monthly during school yearCounty Committees Begin Work On School District Organization; Murle Hayden State Director Dr. Rees Hughes Joins SDofE Staff County Committees College Conference Planned for October Physical Fitness ...
Kansas State Department of Public Instruction
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
The flipped classroom approach has been used as a variation of digital learning even before the covid-19 pandemic. Using this approach and the First Principles of Effective Instruction, this study determined and compared the proving skills of higher ...
Aquino, Ronald L., D, Eduard M. Albay
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source