Results 41 to 50 of about 26,375 (235)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Croatian National Education Standard for Geography - A Review
Kartografija i Geoinformacije, 2006 We are witnesses to the increasing spreading of knowledge in all fields of scholarship and life itself. This has placed a burden on education at all levels.
Dragica Husanović-Pejnović
doaj
The nature of science education: does it cause female students’ disaffection with science [PDF]
, 2000 This thesis seeks to answer the question 'Why are students disaffected with science?' Students' disaffection is described in terms of their dislike for science education.
Read, Marc John Franklin
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Children’s training in projected natural science [PDF]
, 2000 Reikšminiai žodžiai: Gamtamokslinis ugdymas; Projektinis ugdymas; Tarpdalykinė integracija; Tiriamasis darbas; Intersubjective integration; Investigative work; Natural science training; Projected trainingNatural science training is one of the most urgent
Railienė, Laima, Lamanauskas, Vincentas
core
The Benefits and Challenges of Augmented Reality in the Science Classroom: A Narrative Review [PDF]
The use of augmented reality (AR) to facilitate learning in the science classroom is an understudied topic that has only recently begun to be explored. A number of studies performed by academic researchers in science classrooms have indicated that these ...
Taha Mansor Khawaji
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source