Results 101 to 110 of about 1,478,008 (318)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Software Execution Acceleration Using Automatic Instruction Set Extensions [PDF]
, 2013 Jednou z důležitých vlastností aplikačně specifických procesorů je jejich výkon. Aby byl co největší, musí se procesor přizpůsobit potřebám aplikace, kterou bude vykonávat.
Melo, Stanislav
core
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Dynamic Instrumentation Method for Embedded Physical Devices [PDF]
Jisuanji kexueMost existing dynamic instrumentation methods are based on the x86/x64 instruction set,which is poorly compatible with reduced instruction set(RISC) commonly used in embedded devices,and there are problems such as low instrumentation efficiency and large
SI Jianpeng, HONG Zheng, ZHOU Zhenji, CHEN Qian, LI Tao
doaj +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
The helping hand: How to bias kinesthetic aftereffects by instructional set [PDF]
, 1973 Daniel J. Weintraubt, Anita Caplan
openalex +1 more source
Quadsim Version 2.1 Student Manual [PDF]
, 1993 Quadsim is an intermediate code simulator. It allows you to "run" programs that your compiler generates in intermediate code format. Its user interface is similar to most debuggers in that you can step through your program, instruction by instruction ...
Shaban, Marwan
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
The Personalized System of Instruction: Review and Applications to Distance Education
International Review of Research in Open and Distributed Learning, 2003 The present paper (a) outlines the basic features of the Personalized System of Instruction (PSI); (b) provides a brief history of PSI; and (c) describes the application of PSI to distance education.
Lyle K. Grant, Robert E. Spencer
doaj +1 more source