Results 161 to 170 of about 1,478,008 (318)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Known/Chosen Key Attacks against Software Instruction Set Randomization [PDF]
, 2006 Yoav Weiss, Elena Gabriela Barrantes
openalex +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Emulation of a Complex Instruction Set Computer with a Reduced Instruction Set Computer
, 1988 This paper analyzes some of the difficulties of emulating a Complex Instruction Set Computer (CISC) with a Reduced Instruction Set Computer (RISC). It will be shown that although the speed advantage of a RISC is sacrificed, a CISC can be emulated with the exception of software constructs that support nonstandard hardware interfaces.
McNeley, K. J., Milutinovic', V. M.
openaire +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Automatic application-specific instruction-set extensions under microarchitectural constraints
, 2003 Kubilay Atasu, Laura Pozzi, Paolo Ienne
openalex +2 more sources
Performance and energy benefits of instruction set extensions in an FPGA soft core [PDF]
, 2006 Partha Pratim Biswas +4 more
openalex +1 more source
Molecular Oncology, EarlyView.In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
ISEGEN: Generation of High-Quality Instruction Set Extensions by Iterative Improvement
, 2005 Partha Pratim Biswas +4 more
openalex +3 more sources
Automated Instruction Set Characterization and Power Profile Driven Software Optimization for Mobile Devices [PDF]
, 2007 Matthias Grumer +5 more
openalex +1 more source