Results 51 to 60 of about 6,871,078 (322)
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Learning Management System (LMS) Use with Online Instruction
International Journal of Technology in Education, 2020 Learning Management Systems (LMS) reinforce the learning process through online classroom environments. A standard LMS supports an inclusive learning environment for academic progress with interceding structures that promote online collaborative ...
Vaughn Malcolm Bradley
semanticscholar +1 more source
Design modified architecture for MCS-51 with innovated instructions based on VHDL
Ain Shams Engineering Journal, 2013 This paper introduces two new complex instructions over the application with specific instruction set processor. For the MCS-51 family, utilizing a reserved bit, and the unused machine code “A5h” we can modify the conventional instruction set ...
Abd-Elmoneim Mohamed Fouda +1 more
doaj +1 more source
English as a foreign language—teachers’ perspectives on implementing online instruction in the Iranian EFL context [PDF]
Research in Learning Technology, 2014 This study set out to explore Iranian English as a foreign language (EFL) teachers’ perceptions on the implementation of online EFL instruction. A mixed-methods design, including semi-structured interviews and questionnaires, was employed for the ...
Reza Dashtestani
doaj +1 more source
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
General Architecture and Instruction Set Enhancements for Multimedia Applications [PDF]
Journal of Systemics, Cybernetics and Informatics, 2007 The present day multimedia applications (MMAs) are driving the computing industry as every application being developed is using multimedia in one or the other way.
Mansour Assaf, Aparna Rajesh
doaj
Feature instructions improve face-matching accuracy. [PDF]
PLoS ONE, 2018 Identity comparisons of photographs of unfamiliar faces are prone to error but important for applied settings, such as person identification at passport control.
Ahmed M Megreya, Markus Bindemann
doaj +1 more source
Axioms, 2021 In the field of education, the assessment of a student’s learning performance is based on his final course scores. Few people care about what is behind the numbers.
Bor-Tyng Wang
doaj +1 more source