Results 51 to 60 of about 298,312 (311)

Janus: An Uncertain Cache Architecture to Cope with Side Channel Attacks

open access: yes, 2017
Side channel attacks are a major class of attacks to crypto-systems. Attackers collect and analyze timing behavior, I/O data, or power consumption in these systems to undermine their effectiveness in protecting sensitive information.
Darabi, Mostafa   +4 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

High performance extendable instruction set computing [PDF]

open access: yes, 2001
In this paper, a new architecture called the extendable instruction set computer (EISC) is introduced that addresses the issues of memory size and performance in embedded microprocessor systems.
Appelbe, W, Beckett, P, Lee, H
core  

Late allocation and early release of physical registers [PDF]

open access: yes, 2004
The register file is one of the critical components of current processors in terms of access time and power consumption. Among other things, the potential to exploit instruction-level parallelism is closely related to the size and number of ports of the ...
González Colás, Antonio María   +4 more
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Modulo scheduling for a fully-distributed clustered VLIW architecture [PDF]

open access: yes, 2000
Clustering is an approach that many microprocessors are adopting in recent times in order to mitigate the increasing penalties of wire delays. We propose a novel clustered VLIW architecture which has all its resources partitioned among clusters ...
González Colás, Antonio María   +1 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Gated-Attention Architectures for Task-Oriented Language Grounding

open access: yes, 2018
To perform tasks specified by natural language instructions, autonomous agents need to extract semantically meaningful representations of language and map it to visual elements and actions in the environment. This problem is called task-oriented language
Chaplot, Devendra Singh   +4 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Automatic Generation of Interpreter for Multilingual Virtual Machine

open access: yesСовременные информационные технологии и IT-образование, 2021
The article says about existing implementations of interpreter generators and proposes an approach for generating interpreters in assembly for several architectures by describing a set of instructions (BISA - Bytecode Instruction Set Architecture) of a ...
Mark Gonopolskiy
doaj   +1 more source

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