Results 121 to 130 of about 485,814 (306)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Classroom Student Behavior Recognition Using an Intelligent Sensing Framework

IEEE Access
Recognizing classroom student behavior is crucial for evaluating teaching quality and fostering effective learning environments. However, existing methods often rely on teachers’ direct observation or intelligent static image analysis, missing ...
Xian Min Zhao, Farrah Dina Yusop, Hai Chuan Liu, Yeni Nur Prilanita, Yi Xuan Chang   +4 more
doaj   +1 more source

Preparing Teachers for Their Prophetic Role to Serve with Heart, Head, and Hands

, 2007
As teacher preparation programs seek to diversify their pre-service teachers’ exposure to teaching situations, Mount Vernon Nazarene University’s Education Department has discovered how to maximize its freshman’s educational technology field experiences ...
Audeoud, Martine, Harvel, Cindy
core  

The Intersection of Preservice Teachers’ Confidence, Perceptions, and Ideas for Using Instructional Technology for Teaching and Learning [PDF]

, 2013
The evolving landscape of instructional technology is influenced by access to a wide range of technology tools that can be accessed to enhance teaching and learning.
Bennett, Darcie, Gwilliam, Ezra, Howlett, Catherine, Nadelson, Louis, Oswalt, Steve, Sand, Jaime   +5 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Educational Technology in Economics Instruction

Procedia - Social and Behavioral Sciences, 2015
AbstractIn this paper, we will show, in the context of a “market equilibria” example, how the use of educational technology associated with system dynamics makes it possible for instructors to teach undergraduate students topics of economic structures/processes involving nonlinearity, stochasticity, non-differentiability and discontinuity.
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

University students’ acceptance of generative artificial intelligence tools: a mixed-methods study on opinions, attitudes, and behavioral intentions

BMC Psychology
This study examined university students’ acceptance of generative artificial intelligence tools. For this purpose, the research was designed with a sequential explanatory model from mixed research methods.
Özlem Canan Güngören, Duygu Gür Erdoğan, M. Barış Horzum   +2 more
doaj   +1 more source

Evaluating the effectiveness of Nearpod’s interactive science modules on student achievement in Saudi middle schools

Cogent Education
Implementing interactive technology in science education allows students who are not easily engaged to engage, motivates them, and improves their academic performance.
Abdullah Alenezi, Abdulhameed Alenezi
doaj   +1 more source