Results 141 to 150 of about 2,474,852 (293)
Commentary on "targeting versus instrument rules for monetary policy: what is wrong with McCallum and Nelson?" [PDF]
The following are comments in response to Lars Svensson's "Targeting versus Instrument Rules for Monetary Policy: What Is Wrong with McCallum and Nelson?"Monetary ...
Bennett T. McCallum, Edward Nelson
core
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Editorial: Highlights in educational psychology: teacher-student relationship
Claudio Longobardi +2 more
doaj +1 more source
A measurement comparability study to support instrument harmonization in the Canadian Longitudinal Study on Aging. [PDF]
Rafiq T +14 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Video dataset for surgical phase, keypoint, and instrument recognition in laparoscopic surgery (PhaKIR). [PDF]
Rueckert T +8 more
europepmc +1 more source
Instrument Choice in Environmental Policy [PDF]
We examine the extent to which various environmental policy instruments meet major evaluation criteria, including cost-effectiveness, distributional equity, minimization of risk in the presence of uncertainty, and political feasibility.
Parry, Ian W.H., Goulder, Lawrence H.
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