Results 191 to 200 of about 1,949,085 (259)

Reliability and Validity of the Swedish Version of the Parents' Postoperative Pain Measure (PPPM-S): A Cross-Sectional Psychometric Study. [PDF]

Scand J Caring Sci
Hermansson C, Thylén I, Grossmann B.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The Solar Wind Electron (SWE) Instrument for the Interstellar Mapping and Acceleration Probe Mission. [PDF]

Space Sci Rev
Skoug RM, Schultz TB, Venhaus DM, Amaya CE, Choedon T, Christian ER, Crosier RD, De Los Santos A, Fernandes PA, Ford JJ, Gkioulidou M, Hanley JJ, Harvey DS, Hoeper PJ, Kubeczka PW, Liu Y, Martinez JP, McComas DJ, Mohr HD, Nunez C, Pacheco TR, Pope SE, Rodriguez H, Sandoval BF, Schiferl CM, Schwadron NA, Spalsbury LC, Seitz DN, Smith RM, Steinberg JT, Storms SA, Toczynski W, Tyler YD, Vigil VJ.   +33 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Long-Term Efficacy and Safety of GLP-1R Agonist and SGLT2 Inhibitor Therapy in the General Population: A Mendelian Randomization Study. [PDF]

Circ Genom Precis Med
Remala S, Liang L, Shah AM, Buckley LF.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Qualitative validation of TnED©, an electronic instrument capturing pain dimensions in patients with trigeminal neuralgia. [PDF]

J Oral Facial Pain Headache
Tahiri AS, Dodhia SA, Chotaliya S, Ansari H, Garibaldi G, Lasser R, Zakrzewska JM.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Investigating the application value of the "Forward-Deployed Position" model in operating room support by the central sterile supply department. [PDF]

PLoS One
Yang Q, Wang Y, Wu M.
europepmc   +1 more source

The Development, Applications, and Future Directions of Nutritional Literacy Scales: A Scoping Review. [PDF]

Nutrients
Shao H, Huang Z.
europepmc   +1 more source