Results 81 to 90 of about 3,070,130 (304)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Academic writing strategies in university students from three disciplinary areas: design and validation of an instrument

Frontiers in Education
It is acknowledged that writing strategies are highly important not only for their usefulness in the process of text production but also for their value as a learning technique, as they involve the use of cognitive and metacognitive operations.
Sindy Sagredo-Ortiz, Steffanie Kloss
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Predictive factors in the retrieval of endodontic instruments: the relationship between the fragment length and location [PDF]

Restorative Dentistry & Endodontics
ObjectivesThis study aimed to relate the file fragment length and location in the root canal to the retrieval chances, the clinical time required and the occurrence of secondary fractures.Materials and MethodsSixty clinical cases of fractured instruments
Ricardo Portigliatti, Eugenia Pilar Consoli Lizzi, Pablo Alejandro Rodríguez   +2 more
doaj   +1 more source

The Spin-Plane Double Probe Electric Field Instrument for MMS

, 2016
The Spin-plane double probe instrument (SDP) is part of the FIELDS instrument suite of the Magnetospheric Multiscale mission (MMS). Together with the Axial double probe instrument (ADP) and the Electron Drift Instrument (EDI), SDP will measure the 3-D ...
P. Lindqvist, G. Olsson, R. Torbert, B. King, M. Granoff, D. Rau, G. Needell, S. Turco, I. Dors, P. Beckman, J. Macri, C. Frost, J. Salwen, Anders Eriksson, L. Åhlén, Y. Khotyaintsev, J. Porter, K. Lappalainen, R. Ergun, W. Wermeer, S. Tucker   +20 more
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Development of an assessment tool to measure students′ perceptions of respiratory care education programs: Item generation, item reduction, and preliminary validation

Journal of Family and Community Medicine, 2013
Objectives: Students who perceived their learning environment positively are more likely to develop effective learning strategies, and adopt a deep learning approach.
Ghazi Alotaibi, Adel Youssef
doaj   +1 more source

Research Instrument: Instrument Development and Instrument Calibration

Al Hikmah Indonesian Journal of Early Childhood Islamic Education
The development and calibration of research instruments are crucial components in ensuring the accuracy and reliability of data collection in educational and social sciences. This study addresses the issues surrounding the creation and refinement of research instruments, emphasizing the importance of instrument validity and reliability.
Rizal Firdaus, Naf’an Tatihoran, Alip Nuryanto   +2 more
openaire   +1 more source