Results 161 to 170 of about 130,570 (267)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Translation, cross-cultural adaptation, and validation of the Athlete Fear Avoidance Questionnaire into Arabic: A validation study. [PDF]

Medicine (Baltimore)
Alhowimel AS, Aljamaan A, Alhamwan A, Alenazi AM, Alhwoaimel N, Alshehri MM, Alqahtani BA, Alodaibi F, Elnaggar RK.   +8 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Translation, cross-cultural adaptation, and validation into Brazilian Portuguese of the Functional Rhinoplasty Outcome Inventory-17 (FROI-17) for use in patients undergoing Functional Rhinoplasty. [PDF]

Braz J Otorhinolaryngol
Malosá Jorge ME, Soares Silva AC, Quedas A, Malheiros D, Mororo G, Baumann I, Lutaifi Dolci EL, Gutierrez Duran CC.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cross-cultural adaptation and psychometric evaluation of the artificial intelligence learning intention scale (AILIS) among medical sciences students: a methodological study. [PDF]

Med Educ Online
Taghiparast AH, Mahmoudian A, Ghaemi-Amiri M, Ghaffari F.   +3 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Adaptation of the Turkish version of the Undergraduate Clinical Education Environment Measure (UCEEM). [PDF]

BMC Med Educ
Tasdelen Teker G, Can TB, Serefoglu MZ, Delibalta B, Akturan S.   +4 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Cross-cultural adaptation and psychometric evaluation of the dengue preventive attitudes questionnaire for Indonesian public health nurses. [PDF]

BMC Nurs
Hertanti NS, Chuang YH.
europepmc   +1 more source