Results 131 to 140 of about 3,230,793 (311)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Payesh, 2017 Objective (s): Data collection is one of the important stages of research process and requires valid and reliable instruments. The aim of this article was to introduce important steps of translation and construction process of a questionnaire ...
Ziba Taghizadeh +5 more
doaj
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Design and development of a fast scan infrared detection and measurement instrument [PDF]
, 1971 Infrared microscope instrument measures and plots the infrared profile of semiconductor chips, transistors and integrated circuits. Infrared analyses yields information on electrical and physical properties, enabling manufacturing improvements in ...
Dostoomian, A. S. +3 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Development of a new instrument for direct skin friction measurements [PDF]
A device developed for the direct measurement of wall shear stress generated by flows is described. Simple and symmetric in design with optional small moving mass and no internal friction, the features employed in the design eliminate most of the ...
Vakili, A. D., Wu, J. M.
core +1 more source
Towards Research Excellence for Development: The Research Quality plus (RQ+) Assessment Instrument [PDF]
, 2014 This document presents a framework and practical guidelines for assessing the quality of research for development. Referred to as the "RQ+"1 assessment instrument, it serves as a tool to guide the work of external evaluators hired by IDRC as part of the ...
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Establishing cost-effectiveness of genetic targeting of cancer therapies [PDF]
, 2011 The clinical benefit of a new genomic instrument, the 70-gene signature for breast cancer patients, is being evaluated in a randomised clinical trial. The early, controlled implementation process is supported by a Constructive Technology Assessment to ...
Harten, W.H. van +3 more
core +1 more source